STRINGSTRING
TCF7L2 TCF7L2 HMGXB4 HMGXB4 PBRM1 PBRM1 BBX BBX TCF7L1 TCF7L1 CIC CIC HMGB2 HMGB2 SSRP1 SSRP1 SOX4 SOX4 SOX10 SOX10 LOC102355249 LOC102355249 LEF1 LEF1 SOX18 SOX18 SOX1 SOX1 TFAM TFAM SOX2 SOX2 SOX21 SOX21 SOX3 SOX3 HMGB1 HMGB1 LOC102349405 LOC102349405 SOX7 SOX7 CHD3 CHD3 H3AHS5_LATCH H3AHS5_LATCH H3AJR0_LATCH H3AJR0_LATCH KMT2C KMT2C TOX TOX HBP1 HBP1 NSD2 NSD2 LOC102354709 LOC102354709 SOX14 SOX14 TOX2 TOX2 TOX3 TOX3 SMARCE1 SMARCE1 HMGXB3 HMGXB3 TOX4 TOX4 PMS1 PMS1 SOX11 SOX11 HMGB3 HMGB3 SOX17 SOX17 SOX30 SOX30 SOX8 SOX8 TCF7 TCF7 UBTF UBTF SOX6 SOX6 SOX9 SOX9 WDHD1 WDHD1 HMG20A HMG20A SOX5 SOX5 MAEL MAEL
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TCF7L2Transcription factor 7 like 2. (439 aa)
HMGXB4HMG-box containing 4. (570 aa)
PBRM1Polybromo 1. (1496 aa)
BBXBBX high mobility group box domain containing. (951 aa)
TCF7L1Transcription factor 7 like 1. (438 aa)
CICCapicua transcriptional repressor. (2265 aa)
HMGB2High mobility group box 2. (212 aa)
SSRP1FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (584 aa)
SOX4Transcription factor SOX. (385 aa)
SOX10SRY-box transcription factor 10. (451 aa)
LOC102355249SRY-box transcription factor 19a. (281 aa)
LEF1Lymphoid enhancer binding factor 1. (397 aa)
SOX18SRY-box transcription factor 18. (427 aa)
SOX1SRY-box transcription factor 1. (342 aa)
TFAMTranscription factor A, mitochondrial. (277 aa)
SOX2SRY-box transcription factor 2. (315 aa)
SOX21SRY-box transcription factor 21. (247 aa)
SOX3SRY-box transcription factor 3. (304 aa)
HMGB1High mobility group box 1. (216 aa)
LOC102349405Transcription factor SOX. (368 aa)
SOX7SRY-box transcription factor 7. (369 aa)
CHD3Chromodomain helicase DNA binding protein 3. (1975 aa)
H3AHS5_LATCHUncharacterized protein. (725 aa)
H3AJR0_LATCHSRY-box transcription factor 13. (427 aa)
KMT2CLysine methyltransferase 2C. (4872 aa)
TOXThymocyte selection associated high mobility group box. (392 aa)
HBP1HMG-box transcription factor 1. (539 aa)
NSD2Nuclear receptor binding SET domain protein 2. (1348 aa)
LOC102354709HMG box domain-containing protein. (353 aa)
SOX14SRY-box transcription factor 14. (241 aa)
TOX2TOX high mobility group box family member 2. (461 aa)
TOX3TOX high mobility group box family member 3. (540 aa)
SMARCE1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1. (414 aa)
HMGXB3HMG-box containing 3. (1325 aa)
TOX4TOX high mobility group box family member 4. (626 aa)
PMS1PMS1 homolog 1, mismatch repair system component. (1040 aa)
SOX11Transcription factor SOX. (366 aa)
HMGB3High mobility group box 3. (228 aa)
SOX17SRY-box transcription factor 17. (381 aa)
SOX30SRY-box transcription factor 30. (596 aa)
SOX8SRY-box transcription factor 8. (477 aa)
TCF7Transcription factor 7. (343 aa)
UBTFUpstream binding transcription factor. (752 aa)
SOX6SRY-box transcription factor 6. (814 aa)
SOX9SRY-box transcription factor 9. (475 aa)
WDHD1WD repeat and HMG-box DNA binding protein 1. (1137 aa)
HMG20AHigh mobility group 20A. (348 aa)
SOX5SRY-box transcription factor 5. (757 aa)
MAELMaelstrom spermatogenic transposon silencer. (427 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: medium (50%) [HD]