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H2ZTZ4_LATCH H2ZTZ4_LATCH LOC102356451 LOC102356451 PLPP3 PLPP3 DEGS2 DEGS2 SAMD8 SAMD8 SGPP2 SGPP2 KDSR KDSR PRKD2 PRKD2 SPTSSB SPTSSB H3A9H6_LATCH H3A9H6_LATCH PRKD1 PRKD1 CERS5 CERS5 LOC102362617 LOC102362617 PPM1L PPM1L CERT1 CERT1 DEGS1 DEGS1 SPTLC1 SPTLC1 CERS1 CERS1 ALDH3B1 ALDH3B1 PLPP1 PLPP1 SPHK2 SPHK2 LOC102367411 LOC102367411 LOC102349675 LOC102349675 H3AKS1_LATCH H3AKS1_LATCH ACER2 ACER2 SGMS1 SGMS1 LOC102355762 LOC102355762 CERS2 CERS2 ACER1 ACER1 PRKD3 PRKD3 ACER3 ACER3 SGPL1 SGPL1 CSNK1G2 CSNK1G2 PLPP2 PLPP2 SPTLC2 SPTLC2 ORMDL1 ORMDL1 SPTLC3 SPTLC3 LOC102363939 LOC102363939 CSNK1G1 CSNK1G1 ISM1 ISM1 SPHK1 SPHK1 H3BCB4_LATCH H3BCB4_LATCH SGPP1 SGPP1 CERS3 CERS3 SPNS2 SPNS2 ORMDL2 ORMDL2 SGMS2 SGMS2
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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H2ZTZ4_LATCHFatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] (363 aa)
LOC102356451Uncharacterized protein. (208 aa)
PLPP3Phospholipid phosphatase 3. (285 aa)
DEGS2Delta 4-desaturase, sphingolipid 2. (322 aa)
SAMD8Sterile alpha motif domain containing 8. (470 aa)
SGPP2Sphingosine-1-phosphate phosphatase 2. (364 aa)
KDSR3-ketodihydrosphingosine reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (214 aa)
PRKD2Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (831 aa)
SPTSSBSerine palmitoyltransferase, small subunit B. (80 aa)
H3A9H6_LATCHFatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (264 aa)
PRKD1Protein kinase D1. (787 aa)
CERS5Ceramide synthase 5. (392 aa)
LOC102362617Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] (370 aa)
PPM1LProtein phosphatase, Mg2+/Mn2+ dependent 1L. (360 aa)
CERT1Ceramide transporter 1. (624 aa)
DEGS1Delta 4-desaturase, sphingolipid 1. (323 aa)
SPTLC1Serine palmitoyltransferase long chain base subunit 1. (472 aa)
CERS1Ceramide synthase 1. (282 aa)
ALDH3B1Aldehyde dehydrogenase 3 family, member B1; Belongs to the aldehyde dehydrogenase family. (328 aa)
PLPP1Phospholipid phosphatase 1. (283 aa)
SPHK2Sphingosine kinase 2. (479 aa)
LOC102367411Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. (334 aa)
LOC102349675Phosphatidic acid phosphatase type 2D. (329 aa)
H3AKS1_LATCHUncharacterized protein. (107 aa)
ACER2Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (226 aa)
SGMS1Sphingomyelin synthase 1. (412 aa)
LOC102355762Lipid_DES domain-containing protein. (322 aa)
CERS2Ceramide synthase 2. (377 aa)
ACER1Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (272 aa)
PRKD3Protein kinase D3. (797 aa)
ACER3Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (120 aa)
SGPL1Sphingosine-1-phosphate lyase 1. (566 aa)
CSNK1G2Casein kinase 1 gamma 2; Belongs to the protein kinase superfamily. (458 aa)
PLPP2Phospholipid phosphatase 2. (285 aa)
SPTLC2Serine palmitoyltransferase long chain base subunit 2. (532 aa)
ORMDL1ORM1-like protein; Negative regulator of sphingolipid synthesis. (170 aa)
SPTLC3Serine palmitoyltransferase long chain base subunit 3. (551 aa)
LOC102363939ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa)
CSNK1G1Casein kinase 1 gamma 1; Belongs to the protein kinase superfamily. (456 aa)
ISM1Isthmin 1. (439 aa)
SPHK1Sphingosine kinase 1. (508 aa)
H3BCB4_LATCHPAP2_C domain-containing protein. (278 aa)
SGPP1Sphingosine-1-phosphate phosphatase 1. (441 aa)
CERS3Ceramide synthase 3. (349 aa)
SPNS2Sphingolipid transporter 2. (362 aa)
ORMDL2ORM1-like protein; Negative regulator of sphingolipid synthesis. (173 aa)
SGMS2Sphingomyelin synthase 2. (264 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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