12 items (Latimeria chalumnae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PODN	Podocan. (621 aa)
	ELOVL2	Elongation of very long chain fatty acids protein 2; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA). May participate to the production [...] (266 aa)
	ELOVL5	Elongation of very long chain fatty acids protein. (219 aa)
	HSD17B4	Hydroxysteroid 17-beta dehydrogenase 4. (740 aa)
	ELOVL1	Elongation of very long chain fatty acids protein 1; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that [...] (302 aa)
	ACOT8	Acyl-CoA thioesterase 8. (332 aa)
	ACOX1	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (661 aa)
	FADS2	Fatty acid desaturase 2. (445 aa)
	FADS1	Fatty acid desaturase 1. (442 aa)
	ACAA1	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (425 aa)
	PODNL1	Podocan like 1. (599 aa)
	HSDL2	Hydroxysteroid dehydrogenase like 2. (414 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACAA1	ACOT8	ENSLACP00000018116	ENSLACP00000021285	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Acyl-CoA thioesterase 8.	0.470
ACAA1	ACOX1	ENSLACP00000018116	ENSLACP00000019825	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	0.991
ACAA1	HSD17B4	ENSLACP00000018116	ENSLACP00000003889	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Hydroxysteroid 17-beta dehydrogenase 4.	0.965
ACAA1	HSDL2	ENSLACP00000018116	ENSLACP00000012557	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Hydroxysteroid dehydrogenase like 2.	0.973
ACOT8	ACAA1	ENSLACP00000021285	ENSLACP00000018116	Acyl-CoA thioesterase 8.	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	0.470
ACOT8	ACOX1	ENSLACP00000021285	ENSLACP00000019825	Acyl-CoA thioesterase 8.	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	0.546
ACOT8	HSD17B4	ENSLACP00000021285	ENSLACP00000003889	Acyl-CoA thioesterase 8.	Hydroxysteroid 17-beta dehydrogenase 4.	0.477
ACOT8	HSDL2	ENSLACP00000021285	ENSLACP00000012557	Acyl-CoA thioesterase 8.	Hydroxysteroid dehydrogenase like 2.	0.799
ACOX1	ACAA1	ENSLACP00000019825	ENSLACP00000018116	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	0.991
ACOX1	ACOT8	ENSLACP00000019825	ENSLACP00000021285	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	Acyl-CoA thioesterase 8.	0.546
ACOX1	ELOVL2	ENSLACP00000019825	ENSLACP00000007464	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	Elongation of very long chain fatty acids protein 2; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA). May participate to the production [...]	0.531
ACOX1	HSD17B4	ENSLACP00000019825	ENSLACP00000003889	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	Hydroxysteroid 17-beta dehydrogenase 4.	0.973
ACOX1	HSDL2	ENSLACP00000019825	ENSLACP00000012557	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	Hydroxysteroid dehydrogenase like 2.	0.926
ELOVL1	FADS2	ENSLACP00000002564	ENSLACP00000019357	Elongation of very long chain fatty acids protein 1; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that [...]	Fatty acid desaturase 2.	0.526
ELOVL2	ACOX1	ENSLACP00000007464	ENSLACP00000019825	Elongation of very long chain fatty acids protein 2; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA). May participate to the production [...]	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	0.531
ELOVL2	ELOVL5	ENSLACP00000007464	ENSLACP00000006613	Elongation of very long chain fatty acids protein 2; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA). May participate to the production [...]	Elongation of very long chain fatty acids protein.	0.902
ELOVL2	FADS1	ENSLACP00000007464	ENSLACP00000019226	Elongation of very long chain fatty acids protein 2; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA). May participate to the production [...]	Fatty acid desaturase 1.	0.934
ELOVL2	FADS2	ENSLACP00000007464	ENSLACP00000019357	Elongation of very long chain fatty acids protein 2; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA). May participate to the production [...]	Fatty acid desaturase 2.	0.699
ELOVL5	ELOVL2	ENSLACP00000006613	ENSLACP00000007464	Elongation of very long chain fatty acids protein.	Elongation of very long chain fatty acids protein 2; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA). May participate to the production [...]	0.902
ELOVL5	FADS1	ENSLACP00000006613	ENSLACP00000019226	Elongation of very long chain fatty acids protein.	Fatty acid desaturase 1.	0.966