(10 nodes) p75NTR recruits signalling complexes network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NGFR	Nerve growth factor receptor. (197 aa)
	LOC102348796	Uncharacterized protein. (497 aa)
	NGF	Nerve growth factor; Belongs to the NGF-beta family. (272 aa)
	MYD88	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (286 aa)
	H3B6K7_LATCH	IKKbetaNEMObind domain-containing protein. (241 aa)
	IRAK1	Interleukin 1 receptor associated kinase 1. (673 aa)
	SQSTM1	Sequestosome 1. (441 aa)
	RPS27A	Ribosomal protein S27a. (156 aa)
	RIPK2	Receptor interacting serine/threonine kinase 2. (567 aa)
	TRAF6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (559 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
H3B6K7_LATCH	IRAK1	ENSLACP00000017528	ENSLACP00000014884	IKKbetaNEMObind domain-containing protein.	Interleukin 1 receptor associated kinase 1.	0.662
H3B6K7_LATCH	LOC102348796	ENSLACP00000017528	ENSLACP00000023619	IKKbetaNEMObind domain-containing protein.	Uncharacterized protein.	0.431
H3B6K7_LATCH	MYD88	ENSLACP00000017528	ENSLACP00000019094	IKKbetaNEMObind domain-containing protein.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.621
H3B6K7_LATCH	RIPK2	ENSLACP00000017528	ENSLACP00000004499	IKKbetaNEMObind domain-containing protein.	Receptor interacting serine/threonine kinase 2.	0.431
H3B6K7_LATCH	RPS27A	ENSLACP00000017528	ENSLACP00000008678	IKKbetaNEMObind domain-containing protein.	Ribosomal protein S27a.	0.663
H3B6K7_LATCH	SQSTM1	ENSLACP00000017528	ENSLACP00000013831	IKKbetaNEMObind domain-containing protein.	Sequestosome 1.	0.674
H3B6K7_LATCH	TRAF6	ENSLACP00000017528	ENSLACP00000003556	IKKbetaNEMObind domain-containing protein.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.916
IRAK1	H3B6K7_LATCH	ENSLACP00000014884	ENSLACP00000017528	Interleukin 1 receptor associated kinase 1.	IKKbetaNEMObind domain-containing protein.	0.662
IRAK1	LOC102348796	ENSLACP00000014884	ENSLACP00000023619	Interleukin 1 receptor associated kinase 1.	Uncharacterized protein.	0.492
IRAK1	MYD88	ENSLACP00000014884	ENSLACP00000019094	Interleukin 1 receptor associated kinase 1.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.990
IRAK1	RIPK2	ENSLACP00000014884	ENSLACP00000004499	Interleukin 1 receptor associated kinase 1.	Receptor interacting serine/threonine kinase 2.	0.514
IRAK1	RPS27A	ENSLACP00000014884	ENSLACP00000008678	Interleukin 1 receptor associated kinase 1.	Ribosomal protein S27a.	0.630
IRAK1	SQSTM1	ENSLACP00000014884	ENSLACP00000013831	Interleukin 1 receptor associated kinase 1.	Sequestosome 1.	0.772
IRAK1	TRAF6	ENSLACP00000014884	ENSLACP00000003556	Interleukin 1 receptor associated kinase 1.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.999
LOC102348796	H3B6K7_LATCH	ENSLACP00000023619	ENSLACP00000017528	Uncharacterized protein.	IKKbetaNEMObind domain-containing protein.	0.431
LOC102348796	IRAK1	ENSLACP00000023619	ENSLACP00000014884	Uncharacterized protein.	Interleukin 1 receptor associated kinase 1.	0.492
LOC102348796	MYD88	ENSLACP00000023619	ENSLACP00000019094	Uncharacterized protein.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.424
LOC102348796	RIPK2	ENSLACP00000023619	ENSLACP00000004499	Uncharacterized protein.	Receptor interacting serine/threonine kinase 2.	0.900
LOC102348796	RPS27A	ENSLACP00000023619	ENSLACP00000008678	Uncharacterized protein.	Ribosomal protein S27a.	0.452
LOC102348796	TRAF6	ENSLACP00000023619	ENSLACP00000003556	Uncharacterized protein.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.982