(19 nodes) SUMOylation of intracellular receptors network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	VTCN1	V-set domain containing T cell activation inhibitor 1. (279 aa)
	SUMO3	Small ubiquitin-related modifier. (96 aa)
	THRB	Thyroid hormone receptor beta. (397 aa)
	LOC102347040	Ubiquitin-conjugating enzyme E2Ia; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
	THRA	Thyroid hormone receptor alpha. (408 aa)
	H3AQM4_LATCH	Uncharacterized protein. (301 aa)
	LOC102363126	Small ubiquitin-related modifier. (110 aa)
	NR3C2	Uncharacterized protein. (611 aa)
	LOC102350007	Small ubiquitin-related modifier. (100 aa)
	AR	Androgen receptor. (412 aa)
	NR1H2	Nuclear receptor subfamily 1 group H member 2. (426 aa)
	VTCN1-2	Uncharacterized protein. (232 aa)
	NR3C1	Nuclear receptor subfamily 3 group C member 1. (770 aa)
	PIAS1	Protein inhibitor of activated STAT 1. (644 aa)
	PIAS3	Protein inhibitor of activated STAT 3. (645 aa)
	NR1H3	Nuclear receptor subfamily 1 group H member 3. (375 aa)
	PGR	Progesterone receptor. (770 aa)
	PIAS2	Protein inhibitor of activated STAT 2. (564 aa)
	LOC102365863	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AR	H3AQM4_LATCH	ENSLACP00000017054	ENSLACP00000011945	Androgen receptor.	Uncharacterized protein.	0.573
AR	LOC102347040	ENSLACP00000017054	ENSLACP00000008754	Androgen receptor.	Ubiquitin-conjugating enzyme E2Ia; Belongs to the ubiquitin-conjugating enzyme family.	0.521
AR	LOC102350007	ENSLACP00000017054	ENSLACP00000016022	Androgen receptor.	Small ubiquitin-related modifier.	0.605
AR	LOC102365863	ENSLACP00000017054	ENSLACP00000022940	Androgen receptor.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.521
AR	NR3C1	ENSLACP00000017054	ENSLACP00000017638	Androgen receptor.	Nuclear receptor subfamily 3 group C member 1.	0.673
AR	NR3C2	ENSLACP00000017054	ENSLACP00000015400	Androgen receptor.	Uncharacterized protein.	0.955
AR	PGR	ENSLACP00000017054	ENSLACP00000022009	Androgen receptor.	Progesterone receptor.	0.697
AR	PIAS1	ENSLACP00000017054	ENSLACP00000018290	Androgen receptor.	Protein inhibitor of activated STAT 1.	0.501
AR	PIAS2	ENSLACP00000017054	ENSLACP00000022188	Androgen receptor.	Protein inhibitor of activated STAT 2.	0.577
AR	PIAS3	ENSLACP00000017054	ENSLACP00000019717	Androgen receptor.	Protein inhibitor of activated STAT 3.	0.501
H3AQM4_LATCH	AR	ENSLACP00000011945	ENSLACP00000017054	Uncharacterized protein.	Androgen receptor.	0.573
H3AQM4_LATCH	LOC102350007	ENSLACP00000011945	ENSLACP00000016022	Uncharacterized protein.	Small ubiquitin-related modifier.	0.444
H3AQM4_LATCH	NR3C1	ENSLACP00000011945	ENSLACP00000017638	Uncharacterized protein.	Nuclear receptor subfamily 3 group C member 1.	0.754
H3AQM4_LATCH	NR3C2	ENSLACP00000011945	ENSLACP00000015400	Uncharacterized protein.	Uncharacterized protein.	0.900
H3AQM4_LATCH	PGR	ENSLACP00000011945	ENSLACP00000022009	Uncharacterized protein.	Progesterone receptor.	0.608
LOC102347040	AR	ENSLACP00000008754	ENSLACP00000017054	Ubiquitin-conjugating enzyme E2Ia; Belongs to the ubiquitin-conjugating enzyme family.	Androgen receptor.	0.521
LOC102347040	LOC102350007	ENSLACP00000008754	ENSLACP00000016022	Ubiquitin-conjugating enzyme E2Ia; Belongs to the ubiquitin-conjugating enzyme family.	Small ubiquitin-related modifier.	0.997
LOC102347040	LOC102363126	ENSLACP00000008754	ENSLACP00000014332	Ubiquitin-conjugating enzyme E2Ia; Belongs to the ubiquitin-conjugating enzyme family.	Small ubiquitin-related modifier.	0.993
LOC102347040	LOC102365863	ENSLACP00000008754	ENSLACP00000022940	Ubiquitin-conjugating enzyme E2Ia; Belongs to the ubiquitin-conjugating enzyme family.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.900
LOC102347040	PGR	ENSLACP00000008754	ENSLACP00000022009	Ubiquitin-conjugating enzyme E2Ia; Belongs to the ubiquitin-conjugating enzyme family.	Progesterone receptor.	0.403