(29 nodes) Tight junction interactions network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC102365550	Uncharacterized protein. (218 aa)
	LOC102362450	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (192 aa)
	CLDN19	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (209 aa)
	CLDN16	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (255 aa)
	CLDN1	Claudin 1. (210 aa)
	CLDN5	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (213 aa)
	PARD3	Par-3 family cell polarity regulator. (1214 aa)
	CLDN11	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (209 aa)
	CLDN12	Claudin 12. (247 aa)
	PARD6A	Par-6 family cell polarity regulator alpha. (307 aa)
	CLDN20	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (221 aa)
	LOC102362746	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (210 aa)
	LOC102353037	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (233 aa)
	CLDN14	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (235 aa)
	LOC102352776	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (233 aa)
	MPP5	Membrane palmitoylated protein 5; Belongs to the MAGUK family. (678 aa)
	MPDZ	Multiple PDZ domain crumbs cell polarity complex component. (1679 aa)
	PARD6B	Par-6 family cell polarity regulator beta. (369 aa)
	H3AHQ4_LATCH	PB1 domain-containing protein. (116 aa)
	H3ACT9_LATCH	PDZ domain-containing protein. (264 aa)
	H3A9Z9_LATCH	Claudin 23a. (213 aa)
	LOC102365642	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (213 aa)
	CLDN10	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (232 aa)
	LOC106705730	Uncharacterized protein. (200 aa)
	LOC102348536	Uncharacterized protein. (184 aa)
	LOC102348856	Uncharacterized protein. (190 aa)
	PATJ	PATJ crumbs cell polarity complex component. (2073 aa)
	LOC102347948	Uncharacterized protein. (290 aa)
	H2ZTR7_LATCH	Uncharacterized protein. (190 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CLDN1	CLDN10	ENSLACP00000017569	ENSLACP00000005269	Claudin 1.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.675
CLDN1	CLDN11	ENSLACP00000017569	ENSLACP00000016560	Claudin 1.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.714
CLDN1	CLDN12	ENSLACP00000017569	ENSLACP00000016546	Claudin 1.	Claudin 12.	0.626
CLDN1	CLDN14	ENSLACP00000017569	ENSLACP00000012827	Claudin 1.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.704
CLDN1	CLDN19	ENSLACP00000017569	ENSLACP00000020552	Claudin 1.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.671
CLDN1	CLDN20	ENSLACP00000017569	ENSLACP00000014449	Claudin 1.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.664
CLDN1	CLDN5	ENSLACP00000017569	ENSLACP00000017353	Claudin 1.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.784
CLDN1	H3A9Z9_LATCH	ENSLACP00000017569	ENSLACP00000006470	Claudin 1.	Claudin 23a.	0.710
CLDN1	LOC102347948	ENSLACP00000017569	ENSLACP00000001081	Claudin 1.	Uncharacterized protein.	0.476
CLDN1	LOC102348536	ENSLACP00000017569	ENSLACP00000004957	Claudin 1.	Uncharacterized protein.	0.774
CLDN1	LOC102348856	ENSLACP00000017569	ENSLACP00000004079	Claudin 1.	Uncharacterized protein.	0.775
CLDN1	LOC102352776	ENSLACP00000017569	ENSLACP00000012735	Claudin 1.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.694
CLDN1	LOC102353037	ENSLACP00000017569	ENSLACP00000012904	Claudin 1.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.694
CLDN1	LOC102362450	ENSLACP00000017569	ENSLACP00000020610	Claudin 1.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.746
CLDN1	LOC102362746	ENSLACP00000017569	ENSLACP00000014215	Claudin 1.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.761
CLDN1	LOC102365550	ENSLACP00000017569	ENSLACP00000021954	Claudin 1.	Uncharacterized protein.	0.476
CLDN1	LOC102365642	ENSLACP00000017569	ENSLACP00000005344	Claudin 1.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.736
CLDN1	LOC106705730	ENSLACP00000017569	ENSLACP00000005246	Claudin 1.	Uncharacterized protein.	0.750
CLDN1	MPDZ	ENSLACP00000017569	ENSLACP00000009544	Claudin 1.	Multiple PDZ domain crumbs cell polarity complex component.	0.404
CLDN1	PARD3	ENSLACP00000017569	ENSLACP00000017073	Claudin 1.	Par-3 family cell polarity regulator.	0.658