(14 nodes) Activation of the AP-1 family of transcription factors network (Latimeria chalumnae)

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Your Input:
	MAPK11	Mitogen-activated protein kinase. (361 aa)
	FOS	Fos proto-oncogene, AP-1 transcription factor subunit. (391 aa)
	MAPK8	Mitogen-activated protein kinase. (437 aa)
	ATF2	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (495 aa)
	MAPK9	Mitogen-activated protein kinase. (424 aa)
	MAPK14	Mitogen-activated protein kinase. (399 aa)
	H2ZRN5_LATCH	Uncharacterized protein. (172 aa)
	JUN	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (311 aa)
	H3AD77_LATCH	JunE proto-oncogene, AP-1 transcription factor subunit. (316 aa)
	FOSL2	FOS like 2, AP-1 transcription factor subunit. (332 aa)
	MAPK10	Mitogen-activated protein kinase 10. (342 aa)
	ATF7	Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters. (481 aa)
	LOC106703183	C2H2-type domain-containing protein. (189 aa)
	CREB5	cAMP responsive element binding protein 5. (288 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATF2	FOS	ENSLACP00000005304	ENSLACP00000020665	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	Fos proto-oncogene, AP-1 transcription factor subunit.	0.699
ATF2	FOSL2	ENSLACP00000005304	ENSLACP00000008234	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	FOS like 2, AP-1 transcription factor subunit.	0.625
ATF2	H3AD77_LATCH	ENSLACP00000005304	ENSLACP00000007598	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	JunE proto-oncogene, AP-1 transcription factor subunit.	0.844
ATF2	JUN	ENSLACP00000005304	ENSLACP00000005596	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.	0.834
ATF2	LOC106703183	ENSLACP00000005304	ENSLACP00000015636	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	C2H2-type domain-containing protein.	0.453
ATF2	MAPK10	ENSLACP00000005304	ENSLACP00000010110	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	Mitogen-activated protein kinase 10.	0.691
ATF2	MAPK11	ENSLACP00000005304	ENSLACP00000017886	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	Mitogen-activated protein kinase.	0.694
ATF2	MAPK14	ENSLACP00000005304	ENSLACP00000001774	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	Mitogen-activated protein kinase.	0.694
ATF2	MAPK8	ENSLACP00000005304	ENSLACP00000021152	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	Mitogen-activated protein kinase.	0.691
ATF2	MAPK9	ENSLACP00000005304	ENSLACP00000002488	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	Mitogen-activated protein kinase.	0.690
ATF7	CREB5	ENSLACP00000013728	ENSLACP00000017246	Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters.	cAMP responsive element binding protein 5.	0.430
ATF7	FOS	ENSLACP00000013728	ENSLACP00000020665	Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters.	Fos proto-oncogene, AP-1 transcription factor subunit.	0.699
ATF7	FOSL2	ENSLACP00000013728	ENSLACP00000008234	Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters.	FOS like 2, AP-1 transcription factor subunit.	0.625
ATF7	H3AD77_LATCH	ENSLACP00000013728	ENSLACP00000007598	Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters.	JunE proto-oncogene, AP-1 transcription factor subunit.	0.816
ATF7	JUN	ENSLACP00000013728	ENSLACP00000005596	Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters.	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.	0.816
ATF7	LOC106703183	ENSLACP00000013728	ENSLACP00000015636	Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters.	C2H2-type domain-containing protein.	0.453
ATF7	MAPK10	ENSLACP00000013728	ENSLACP00000010110	Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters.	Mitogen-activated protein kinase 10.	0.691
ATF7	MAPK11	ENSLACP00000013728	ENSLACP00000017886	Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters.	Mitogen-activated protein kinase.	0.694
ATF7	MAPK14	ENSLACP00000013728	ENSLACP00000001774	Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters.	Mitogen-activated protein kinase.	0.694
ATF7	MAPK8	ENSLACP00000013728	ENSLACP00000021152	Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters.	Mitogen-activated protein kinase.	0.691