(6 nodes) CASP8 activity is inhibited network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TRADD	Death domain-containing protein. (313 aa)
	LOC102359774	Uncharacterized protein. (218 aa)
	RIPK1	Receptor interacting serine/threonine kinase 1. (667 aa)
	FADD	Fas associated via death domain. (193 aa)
	FAS	Uncharacterized protein. (330 aa)
	FASLG	Fas ligand. (261 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FADD	FAS	ENSLACP00000009943	ENSLACP00000006425	Fas associated via death domain.	Uncharacterized protein.	0.999
FADD	FASLG	ENSLACP00000009943	ENSLACP00000017423	Fas associated via death domain.	Fas ligand.	0.962
FADD	LOC102359774	ENSLACP00000009943	ENSLACP00000017377	Fas associated via death domain.	Uncharacterized protein.	0.965
FADD	RIPK1	ENSLACP00000009943	ENSLACP00000011259	Fas associated via death domain.	Receptor interacting serine/threonine kinase 1.	0.995
FADD	TRADD	ENSLACP00000009943	ENSLACP00000017534	Fas associated via death domain.	Death domain-containing protein.	0.999
FAS	FADD	ENSLACP00000006425	ENSLACP00000009943	Uncharacterized protein.	Fas associated via death domain.	0.999
FAS	FASLG	ENSLACP00000006425	ENSLACP00000017423	Uncharacterized protein.	Fas ligand.	0.997
FAS	LOC102359774	ENSLACP00000006425	ENSLACP00000017377	Uncharacterized protein.	Uncharacterized protein.	0.851
FAS	RIPK1	ENSLACP00000006425	ENSLACP00000011259	Uncharacterized protein.	Receptor interacting serine/threonine kinase 1.	0.847
FAS	TRADD	ENSLACP00000006425	ENSLACP00000017534	Uncharacterized protein.	Death domain-containing protein.	0.840
FASLG	FADD	ENSLACP00000017423	ENSLACP00000009943	Fas ligand.	Fas associated via death domain.	0.962
FASLG	FAS	ENSLACP00000017423	ENSLACP00000006425	Fas ligand.	Uncharacterized protein.	0.997
FASLG	LOC102359774	ENSLACP00000017423	ENSLACP00000017377	Fas ligand.	Uncharacterized protein.	0.684
FASLG	RIPK1	ENSLACP00000017423	ENSLACP00000011259	Fas ligand.	Receptor interacting serine/threonine kinase 1.	0.730
FASLG	TRADD	ENSLACP00000017423	ENSLACP00000017534	Fas ligand.	Death domain-containing protein.	0.830
LOC102359774	FADD	ENSLACP00000017377	ENSLACP00000009943	Uncharacterized protein.	Fas associated via death domain.	0.965
LOC102359774	FAS	ENSLACP00000017377	ENSLACP00000006425	Uncharacterized protein.	Uncharacterized protein.	0.851
LOC102359774	FASLG	ENSLACP00000017377	ENSLACP00000017423	Uncharacterized protein.	Fas ligand.	0.684
LOC102359774	RIPK1	ENSLACP00000017377	ENSLACP00000011259	Uncharacterized protein.	Receptor interacting serine/threonine kinase 1.	0.888
LOC102359774	TRADD	ENSLACP00000017377	ENSLACP00000017534	Uncharacterized protein.	Death domain-containing protein.	0.869