STRINGSTRING
CTDP1 CTDP1 EAF1 EAF1 LOC102354876 LOC102354876 H3AV84_LATCH H3AV84_LATCH LOC102353559 LOC102353559 POLR2A POLR2A TAF12 TAF12 CCNK CCNK POLR2E POLR2E NCBP1 NCBP1 TAF11 TAF11 ERCC2 ERCC2 M3XKT3_LATCH M3XKT3_LATCH LOC102365978 LOC102365978 GTF2H3 GTF2H3 TBPL2 TBPL2 SLC39A13 SLC39A13 MNAT1 MNAT1 CTR9 CTR9 GTF2A2 GTF2A2 TCEANC TCEANC NELFCD NELFCD ERCC3 ERCC3 POLR2H POLR2H H3B5R9_LATCH H3B5R9_LATCH IWS1 IWS1 SPAG16 SPAG16 GTF2E1 GTF2E1 POLR2K POLR2K CDK7 CDK7 GTF2A1 GTF2A1 TCEA1 TCEA1 SUPT4H1 SUPT4H1 NELFB NELFB CDK9 CDK9 TAF7 TAF7 POLR2D POLR2D NCBP2 NCBP2 CCNT1 CCNT1 POLR2L POLR2L H3AS02_LATCH H3AS02_LATCH POLR2G POLR2G TCEA2 TCEA2 CCNQ CCNQ CINP CINP PRF1 PRF1 H3A8J5_LATCH H3A8J5_LATCH TAF3 TAF3 TBP TBP WDR61 WDR61 TAF13 TAF13 H3A5P2_LATCH H3A5P2_LATCH SUPT16H SUPT16H TAF10 TAF10 H3A4B5_LATCH H3A4B5_LATCH POLR2F POLR2F LEO1 LEO1 RTF1 RTF1 POLR2C POLR2C TAF5L TAF5L SSRP1 SSRP1 MLLT3 MLLT3 SUPT6H SUPT6H GTF2E2 GTF2E2 TAF6 TAF6 POLR2B POLR2B CCNH CCNH TAF5 TAF5 NELFE NELFE LOC102361278 LOC102361278 H2ZXQ6_LATCH H2ZXQ6_LATCH LOC102365546 LOC102365546 CDC73 CDC73 H2ZV13_LATCH H2ZV13_LATCH H2ZTI8_LATCH H2ZTI8_LATCH LOC102356836 LOC102356836 TAF4 TAF4 TBPL1 TBPL1 CCNT2 CCNT2 GTF2B GTF2B LOC102355331 LOC102355331 GTF2F1 GTF2F1 AFF4 AFF4 GTF2H4 GTF2H4 EAF2 EAF2 SUPT5H SUPT5H TAF9 TAF9 LOC102359646 LOC102359646 TCEANC2 TCEANC2 AFF1 AFF1 TCEA3 TCEA3 ELOA ELOA TAF4B TAF4B TAF2 TAF2 POLR2I POLR2I GTF2H1 GTF2H1 PAF1 PAF1 ELOC ELOC MLLT1 MLLT1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CTDP1RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (846 aa)
EAF1ELL associated factor 1. (260 aa)
LOC102354876Si:dkey-12j5.1. (292 aa)
H3AV84_LATCHTAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (1561 aa)
LOC102353559General transcription factor IIH subunit. (393 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1920 aa)
TAF12TATA-box binding protein associated factor 12. (217 aa)
CCNKCyclin K; Belongs to the cyclin family. (605 aa)
POLR2ERNA polymerase II subunit E. (210 aa)
NCBP1Nuclear cap binding protein subunit 1. (804 aa)
TAF11TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (209 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (611 aa)
M3XKT3_LATCHRNA_pol_L_2 domain-containing protein. (105 aa)
LOC102365978Uncharacterized protein. (541 aa)
GTF2H3General transcription factor IIH subunit 3. (330 aa)
TBPL2TATA-box binding protein like 2. (344 aa)
SLC39A13Solute carrier family 39 member 13. (312 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
CTR9CTR9 homolog, Paf1/RNA polymerase II complex component. (1163 aa)
GTF2A2Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (109 aa)
TCEANCTranscription elongation factor A N-terminal and central domain containing. (363 aa)
NELFCDNegative elongation factor complex member C/D. (596 aa)
ERCC3ERCC excision repair 3, TFIIH core complex helicase subunit. (795 aa)
POLR2HDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
H3B5R9_LATCHNuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (156 aa)
IWS1Interacts with SUPT6H, CTD assembly factor 1. (796 aa)
SPAG16WD_REPEATS_REGION domain-containing protein. (608 aa)
GTF2E1General transcription factor IIE subunit 1. (449 aa)
POLR2KRNA polymerase II subunit K. (59 aa)
CDK7Cyclin dependent kinase 7. (210 aa)
GTF2A1General transcription factor IIA subunit 1. (388 aa)
TCEA1Transcription elongation factor A1. (181 aa)
SUPT4H1Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family. (117 aa)
NELFBNegative elongation factor complex member B. (577 aa)
CDK9Cyclin dependent kinase 9; Belongs to the protein kinase superfamily. (372 aa)
TAF7TATA-box binding protein associated factor 7. (366 aa)
POLR2DRNA polymerase II subunit D. (142 aa)
NCBP2Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (164 aa)
CCNT1Cyclin T1; Belongs to the cyclin family. (731 aa)
POLR2LRNA polymerase II subunit L. (67 aa)
H3AS02_LATCHUncharacterized protein. (291 aa)
POLR2GRNA polymerase II subunit G. (172 aa)
TCEA2Transcription elongation factor A2. (327 aa)
CCNQCyclin Q; Belongs to the cyclin family. (247 aa)
CINPCyclin dependent kinase 2 interacting protein. (212 aa)
PRF1Uncharacterized protein. (546 aa)
H3A8J5_LATCHUncharacterized protein. (241 aa)
TAF3TATA-box binding protein associated factor 3. (795 aa)
TBPTATA-box binding protein. (301 aa)
WDR61WD_REPEATS_REGION domain-containing protein. (305 aa)
TAF13TATA-box binding protein associated factor 13. (124 aa)
H3A5P2_LATCHWD_REPEATS_REGION domain-containing protein. (253 aa)
SUPT16HSPT16 homolog, facilitates chromatin remodeling subunit. (1044 aa)
TAF10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (142 aa)
H3A4B5_LATCHTFIIS N-terminal domain-containing protein. (631 aa)
POLR2FRNA polymerase II subunit F. (127 aa)
LEO1LEO1 homolog, Paf1/RNA polymerase II complex component. (674 aa)
RTF1RTF1 homolog, Paf1/RNA polymerase II complex component. (528 aa)
POLR2CRNA polymerase II subunit C. (323 aa)
TAF5LTATA-box binding protein associated factor 5 like. (564 aa)
SSRP1FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (584 aa)
MLLT3Uncharacterized protein. (61 aa)
SUPT6HTranscription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1719 aa)
GTF2E2Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (292 aa)
TAF6TATA-box binding protein associated factor 6. (675 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1176 aa)
CCNHCyclin H; Belongs to the cyclin family. (329 aa)
TAF5TATA-box binding protein associated factor 5. (622 aa)
NELFENegative elongation factor complex member E. (344 aa)
LOC102361278Si:dkey-219c3.2. (1070 aa)
H2ZXQ6_LATCHUncharacterized protein. (555 aa)
LOC102365546Uncharacterized protein. (540 aa)
CDC73Cell division cycle 73. (316 aa)
H2ZV13_LATCHUncharacterized protein. (138 aa)
H2ZTI8_LATCHC2 domain-containing protein. (481 aa)
LOC102356836Uncharacterized protein. (543 aa)
TAF4TATA-box binding protein associated factor 4. (830 aa)
TBPL1TATA-box binding protein like 1. (124 aa)
CCNT2Cyclin T2; Belongs to the cyclin family. (750 aa)
GTF2BGeneral transcription factor IIB. (316 aa)
LOC102355331HTH TFE/IIEalpha-type domain-containing protein. (426 aa)
GTF2F1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (525 aa)
AFF4AF4/FMR2 family member 4. (1163 aa)
GTF2H4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (461 aa)
EAF2ELL associated factor 2. (257 aa)
SUPT5HTranscription elongation factor SPT5. (1081 aa)
TAF9TATA-box binding protein associated factor 9. (251 aa)
LOC102359646MLLT3 super elongation complex subunit. (566 aa)
TCEANC2Uncharacterized protein. (208 aa)
AFF1AF4/FMR2 family member 1. (1215 aa)
TCEA3Transcription elongation factor A3. (429 aa)
ELOATFIIS N-terminal domain-containing protein. (805 aa)
TAF4BTATA-box binding protein associated factor 4b. (688 aa)
TAF2TATA-box binding protein associated factor 2. (1039 aa)
POLR2IDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
GTF2H1General transcription factor IIH subunit 1. (548 aa)
PAF1PAF1 homolog, Paf1/RNA polymerase II complex component. (530 aa)
ELOCElongin C; Belongs to the SKP1 family. (113 aa)
MLLT1MLLT1 super elongation complex subunit. (488 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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