STRINGSTRING
FANCD2 FANCD2 USP1 USP1 LOC102346166 LOC102346166 LOC102350907 LOC102350907 FANCF FANCF FANCB FANCB LOC102355250 LOC102355250 FAAP24 FAAP24 RPA1 RPA1 RPS27A RPS27A WDR48 WDR48 FANCM FANCM KXD1 KXD1 RPA3 RPA3 FANCL FANCL ATR ATR PROSER1 PROSER1 FANCA FANCA MUS81 MUS81 H3AZT0_LATCH H3AZT0_LATCH EME2 EME2 SLX4 SLX4 UBE2T UBE2T DCLRE1B DCLRE1B NUTF2 NUTF2 FANCI FANCI FAN1 FAN1 ATRIP ATRIP DCLRE1A DCLRE1A EME1 EME1 MEIOB MEIOB CENPX CENPX
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FANCD2FA complementation group D2. (1462 aa)
USP1Ubiquitin specific peptidase 1; Belongs to the peptidase C19 family. (739 aa)
LOC102346166Ubiquitin-like domain-containing protein. (95 aa)
LOC102350907Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
FANCFFA complementation group F. (337 aa)
FANCBFA complementation group B. (850 aa)
LOC102355250Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (264 aa)
FAAP24FA core complex associated protein 24. (217 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (495 aa)
RPS27ARibosomal protein S27a. (156 aa)
WDR48WD repeat domain 48. (677 aa)
FANCMFA complementation group M. (2075 aa)
KXD1Ubiquitin-like domain-containing protein. (231 aa)
RPA3Replication protein A3. (121 aa)
FANCLFA complementation group L. (367 aa)
ATRATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2654 aa)
PROSER1Proline and serine rich 1. (959 aa)
FANCAFA complementation group A. (1436 aa)
MUS81Uncharacterized protein. (421 aa)
H3AZT0_LATCHUncharacterized protein. (114 aa)
EME2Essential meiotic structure-specific endonuclease subunit 2. (299 aa)
SLX4BTB domain-containing protein. (1393 aa)
UBE2TUbiquitin conjugating enzyme E2 T; Belongs to the ubiquitin-conjugating enzyme family. (199 aa)
DCLRE1BDNA cross-link repair 1B. (369 aa)
NUTF2Nuclear transport factor 2. (127 aa)
FANCIFA complementation group I. (1338 aa)
FAN1Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (1098 aa)
ATRIPATR interacting protein. (782 aa)
DCLRE1ADNA cross-link repair 1A. (1028 aa)
EME1Essential meiotic structure-specific endonuclease 1. (609 aa)
MEIOBMeiosis specific with OB-fold. (470 aa)
CENPXUncharacterized protein. (81 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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