STRINGSTRING
DAXX DAXX CCNA2 CCNA2 TXNDC11 TXNDC11 LOC102346166 LOC102346166 LOC102350907 LOC102350907 USP7 USP7 AKT1 AKT1 ATM ATM RICTOR RICTOR CCNA1 CCNA1 RPS27A RPS27A LOC102367189 LOC102367189 KXD1 KXD1 LOC102350821 LOC102350821 MDM2 MDM2 CCNG1 CCNG1 PPP2R1A PPP2R1A TP53 TP53 H3B8U3_LATCH H3B8U3_LATCH PPP2CA PPP2CA MLST8 MLST8 MTOR MTOR MDM4 MDM4 MAPKAP1 MAPKAP1 RNF34 RNF34 RFFL RFFL PPP2R1B PPP2R1B AKT2 AKT2 CDK2 CDK2 CDK1 CDK1 AKT3 AKT3 PDPK1 PDPK1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DAXXDeath-domain associated protein. (728 aa)
CCNA2Cyclin A2; Belongs to the cyclin family. (447 aa)
TXNDC11Thioredoxin domain containing 11. (738 aa)
LOC102346166Ubiquitin-like domain-containing protein. (95 aa)
LOC102350907Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
USP7Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family. (1101 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (478 aa)
ATMATM serine/threonine kinase. (2375 aa)
RICTORRPTOR independent companion of MTOR complex 2. (1664 aa)
CCNA1Cyclin A1; Belongs to the cyclin family. (433 aa)
RPS27ARibosomal protein S27a. (156 aa)
LOC102367189Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (342 aa)
KXD1Ubiquitin-like domain-containing protein. (231 aa)
LOC102350821Serine/threonine-protein phosphatase. (309 aa)
MDM2E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (485 aa)
CCNG1Cyclin G1; Belongs to the cyclin family. (296 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (591 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (401 aa)
H3B8U3_LATCHSerine/threonine-protein kinase TOR. (1418 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
MLST8MTOR associated protein, LST8 homolog. (326 aa)
MTORMechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family. (1009 aa)
MDM4Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. (491 aa)
MAPKAP1MAPK associated protein 1. (523 aa)
RNF34Ring finger protein 34. (384 aa)
RFFLRing finger and FYVE-like domain containing E3 ubiquitin protein ligase. (361 aa)
PPP2R1BProtein phosphatase 2 scaffold subunit Abeta. (589 aa)
AKT2AKT serine/threonine kinase 2; Belongs to the protein kinase superfamily. (488 aa)
CDK2Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa)
CDK1Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (302 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (470 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (563 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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