(47 nodes) Metabolism of fat-soluble vitamins network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PYROXD2	Pyridine nucleotide-disulphide oxidoreductase domain 2. (583 aa)
	LRP10	LDL receptor related protein 10. (543 aa)
	RBP4	Retinol binding protein 4; Belongs to the calycin superfamily. Lipocalin family. (201 aa)
	BCO2	Beta-carotene oxygenase 2. (558 aa)
	LOC102361871	Uncharacterized protein. (1880 aa)
	H3B5Q5_LATCH	Lipase_GDSL domain-containing protein. (388 aa)
	H3B4X5_LATCH	Uncharacterized protein. (1753 aa)
	APOA4	Apolipoprotein A4. (367 aa)
	BCO1	Beta-carotene oxygenase 1. (531 aa)
	H2ZS43_LATCH	DUF1943 domain-containing protein. (325 aa)
	GPC1	Glypican 1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (552 aa)
	LRP1B	Uncharacterized protein. (1007 aa)
	LOC102352186	Vitellogenin domain-containing protein. (463 aa)
	LRP12	LDL receptor related protein 12. (534 aa)
	H2ZXK1_LATCH	Uncharacterized protein. (547 aa)
	HSPG2	Heparan sulfate proteoglycan 2. (2595 aa)
	APOM	Apolipoprotein M. (194 aa)
	H3A5Z1_LATCH	Uncharacterized protein. (223 aa)
	LOC102365332	Apolipoprotein Ea. (278 aa)
	LOC102365063	Apolipoprotein A-IV b, tandem duplicate 2. (252 aa)
	TTPAL	Alpha tocopherol transfer protein like. (340 aa)
	LOC102360472	Si:ch1073-13h15.3. (492 aa)
	LOC102357889	Uncharacterized protein. (1826 aa)
	H3AZB0_LATCH	Glypican 5c; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (263 aa)
	H3AY50_LATCH	Retinol saturase (all-trans-retinol 13,14-reductase). (515 aa)
	LOC102348686	Uncharacterized protein. (591 aa)
	RBP7	Retinol binding protein 7; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (133 aa)
	H3ABE1_LATCH	Uncharacterized protein. (86 aa)
	H3ACY2_LATCH	Uncharacterized protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (134 aa)
	GPC2	Glypican 2; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (477 aa)
	RBP1	Retinol binding protein 1; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (135 aa)
	SDC3	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (416 aa)
	PLB1	Phospholipase B1. (967 aa)
	RBP2	Retinol binding protein 2; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (135 aa)
	LOC102357927	VKc domain-containing protein. (176 aa)
	LRP3	LDL receptor related protein 3. (692 aa)
	GPC6	Uncharacterized protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (178 aa)
	TTR	Transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. (149 aa)
	APOB	Apolipoprotein B. (4644 aa)
	UBIAD1	UbiA prenyltransferase domain containing 1. (368 aa)
	APOA1	Uncharacterized protein. (237 aa)
	VKORC1L1	Vitamin K epoxide reductase complex subunit 1 like 1. (175 aa)
	LRP1	LDL receptor related protein 1. (4329 aa)
	AGRN	Agrin. (1882 aa)
	H3BFA3_LATCH	NtA domain-containing protein. (154 aa)
	GPC4	Glypican 4; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (433 aa)
	GPC3	Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (270 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGRN	APOB	ENSLACP00000020835	ENSLACP00000022987	Agrin.	Apolipoprotein B.	0.528
AGRN	H3A5Z1_LATCH	ENSLACP00000020835	ENSLACP00000005062	Agrin.	Uncharacterized protein.	0.564
AGRN	H3ABE1_LATCH	ENSLACP00000020835	ENSLACP00000006962	Agrin.	Uncharacterized protein.	0.580
AGRN	H3BFA3_LATCH	ENSLACP00000020835	ENSLACP00000020574	Agrin.	NtA domain-containing protein.	0.900
AGRN	HSPG2	ENSLACP00000020835	ENSLACP00000002678	Agrin.	Heparan sulfate proteoglycan 2.	0.726
AGRN	LOC102348686	ENSLACP00000020835	ENSLACP00000012400	Agrin.	Uncharacterized protein.	0.564
AGRN	LOC102365332	ENSLACP00000020835	ENSLACP00000016337	Agrin.	Apolipoprotein Ea.	0.555
AGRN	LRP1	ENSLACP00000020835	ENSLACP00000021100	Agrin.	LDL receptor related protein 1.	0.580
AGRN	LRP10	ENSLACP00000020835	ENSLACP00000019130	Agrin.	LDL receptor related protein 10.	0.443
AGRN	LRP12	ENSLACP00000020835	ENSLACP00000001633	Agrin.	LDL receptor related protein 12.	0.443
AGRN	LRP1B	ENSLACP00000020835	ENSLACP00000001391	Agrin.	Uncharacterized protein.	0.580
AGRN	LRP3	ENSLACP00000020835	ENSLACP00000010885	Agrin.	LDL receptor related protein 3.	0.443
AGRN	SDC3	ENSLACP00000020835	ENSLACP00000019697	Agrin.	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.	0.490
APOA1	APOA4	ENSLACP00000022439	ENSLACP00000016757	Uncharacterized protein.	Apolipoprotein A4.	0.674
APOA1	APOB	ENSLACP00000022439	ENSLACP00000022987	Uncharacterized protein.	Apolipoprotein B.	0.850
APOA1	H2ZS43_LATCH	ENSLACP00000022439	ENSLACP00000000214	Uncharacterized protein.	DUF1943 domain-containing protein.	0.663
APOA1	H2ZXK1_LATCH	ENSLACP00000022439	ENSLACP00000002122	Uncharacterized protein.	Uncharacterized protein.	0.663
APOA1	H3B4X5_LATCH	ENSLACP00000022439	ENSLACP00000016946	Uncharacterized protein.	Uncharacterized protein.	0.597
APOA1	LOC102352186	ENSLACP00000022439	ENSLACP00000001439	Uncharacterized protein.	Vitellogenin domain-containing protein.	0.663
APOA1	LOC102357889	ENSLACP00000022439	ENSLACP00000015287	Uncharacterized protein.	Uncharacterized protein.	0.597