STRINGSTRING
H3AMA4_LATCH H3AMA4_LATCH LOC102350821 LOC102350821 H3AMG4_LATCH H3AMG4_LATCH CD28 CD28 PPP4R1 PPP4R1 FGF16 FGF16 FGF22 FGF22 RELCH RELCH WDR64 WDR64 FGF13 FGF13 LOC102362077 LOC102362077 LOC102351332 LOC102351332 PPP2R1A PPP2R1A FGF3 FGF3 PIP4K2A PIP4K2A H3AWX7_LATCH H3AWX7_LATCH FGF4 FGF4 FGF19 FGF19 RHOG RHOG FGF20 FGF20 IRAK1 IRAK1 PIK3CB PIK3CB FGF1 FGF1 H3B032_LATCH H3B032_LATCH MET MET FGFR1 FGFR1 FGF18 FGF18 PIK3R1 PIK3R1 NRG2 NRG2 FNDC3B FNDC3B FGF7 FGF7 PIP5K1B PIP5K1B PIP5K1C PIP5K1C PDGFRB PDGFRB FGF5 FGF5 ERBB2 ERBB2 PIK3CA PIK3CA CD276 CD276 FAM102B FAM102B IL1RAP IL1RAP IRAK4 IRAK4 FAM102A FAM102A H3B9M3_LATCH H3B9M3_LATCH PPP2CA PPP2CA FGF2 FGF2 PPP2R5E PPP2R5E TGFA TGFA FGF23 FGF23 FGF6 FGF6 PIP4K2C PIP4K2C LOC102352712 LOC102352712 PPP2R1B PPP2R1B FNBP4 FNBP4 PPP4R4 PPP4R4 FGFR4 FGFR4 PDGFA PDGFA ESR2 ESR2 M3XIM8_LATCH M3XIM8_LATCH PPP2R5D PPP2R5D PPP2R5C PPP2R5C STRN STRN HGF HGF PIP5KL1 PIP5KL1 MORN2 MORN2 FGFR3 FGFR3 GRB2 GRB2 NRG1 NRG1 ERBB4 ERBB4 ERBB3 ERBB3 FNDC3A FNDC3A STRN4 STRN4 PDGFB PDGFB LOC102357602 LOC102357602 TRAF6 TRAF6 PIP4K2B PIP4K2B BTC BTC LOC102364515 LOC102364515 ERBB4-2 ERBB4-2 KIT KIT GAB2 GAB2 EPGN EPGN H3A7N7_LATCH H3A7N7_LATCH INSC INSC LOC102356182 LOC102356182 HBEGF HBEGF FRS2 FRS2 PTPN11 PTPN11 LOC102350355 LOC102350355 H3ACE0_LATCH H3ACE0_LATCH FGFR2 FGFR2 FGF8 FGF8 LOC102361473 LOC102361473 PIP5K1A PIP5K1A LOC102348007 LOC102348007 AREG AREG PPP2R5B PPP2R5B GAB1 GAB1 LOC102349237 LOC102349237 PIK3CD PIK3CD PIK3AP1 PIK3AP1 PDGFRA PDGFRA STRN3 STRN3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
H3AMA4_LATCHUncharacterized protein. (373 aa)
LOC102350821Serine/threonine-protein phosphatase. (309 aa)
H3AMG4_LATCHUncharacterized protein. (141 aa)
CD28Ig-like domain-containing protein. (202 aa)
PPP4R1Protein phosphatase 4 regulatory subunit 1. (765 aa)
FGF16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
FGF22Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (99 aa)
RELCHRAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1037 aa)
WDR64WD repeat domain 64. (799 aa)
FGF13Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (255 aa)
LOC102362077Ras homolog gene family, member Gc. (192 aa)
LOC102351332Zgc:158659; Belongs to the PI3/PI4-kinase family. (1067 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (591 aa)
FGF3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (237 aa)
PIP4K2APhosphatidylinositol-5-phosphate 4-kinase type 2 alpha. (334 aa)
H3AWX7_LATCHCrystallin, beta B1, like 3; Belongs to the beta/gamma-crystallin family. (211 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (195 aa)
FGF19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (217 aa)
RHOGRas homolog family member G. (191 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
IRAK1Interleukin 1 receptor associated kinase 1. (673 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1077 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
H3B032_LATCHC2 NT-type domain-containing protein. (394 aa)
METMET proto-oncogene, receptor tyrosine kinase. (1385 aa)
FGFR1Fibroblast growth factor receptor. (824 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (725 aa)
NRG2Neuregulin 2. (429 aa)
FNDC3BFibronectin type III domain containing 3B. (944 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
PIP5K1BPhosphatidylinositol-4-phosphate 5-kinase type 1 beta. (501 aa)
PIP5K1CPhosphatidylinositol-4-phosphate 5-kinase type 1 gamma. (646 aa)
PDGFRBPlatelet derived growth factor receptor beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1103 aa)
FGF5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
ERBB2Receptor protein-tyrosine kinase. (1250 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1069 aa)
CD276CD276 molecule. (324 aa)
FAM102BC2 NT-type domain-containing protein. (366 aa)
IL1RAPInterleukin 1 receptor accessory protein. (688 aa)
IRAK4Interleukin 1 receptor associated kinase 4. (454 aa)
FAM102AFamily with sequence similarity 102 member A. (412 aa)
H3B9M3_LATCHWD_REPEATS_REGION domain-containing protein. (629 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
PPP2R5ESerine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (467 aa)
TGFATransforming growth factor alpha. (140 aa)
FGF23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (249 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
PIP4K2CPhosphatidylinositol-5-phosphate 4-kinase type 2 gamma. (305 aa)
LOC102352712Protein tyrosine phosphatase non-receptor type 11b. (553 aa)
PPP2R1BProtein phosphatase 2 scaffold subunit Abeta. (589 aa)
FNBP4Formin binding protein 4. (1022 aa)
PPP4R4Protein phosphatase 4 regulatory subunit 4. (864 aa)
FGFR4Fibroblast growth factor receptor. (810 aa)
PDGFAPlatelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (197 aa)
ESR2Estrogen receptor 2. (583 aa)
M3XIM8_LATCHIg-like domain-containing protein. (241 aa)
PPP2R5DSerine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (619 aa)
PPP2R5CSerine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (610 aa)
STRNStriatin. (789 aa)
HGFHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (720 aa)
PIP5KL1Phosphatidylinositol-4-phosphate 5-kinase like 1. (437 aa)
MORN2MORN repeat containing 2. (79 aa)
FGFR3Fibroblast growth factor receptor. (778 aa)
GRB2Growth factor receptor bound protein 2. (292 aa)
NRG1Neuregulin 1. (409 aa)
ERBB4Protein kinase domain-containing protein. (479 aa)
ERBB3Protein kinase domain-containing protein. (1047 aa)
FNDC3AFibronectin type III domain containing 3A. (1198 aa)
STRN4Striatin 4. (715 aa)
PDGFBPDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (209 aa)
LOC102357602Uncharacterized protein. (139 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (559 aa)
PIP4K2BPhosphatidylinositol-5-phosphate 4-kinase type 2 beta. (372 aa)
BTCEGF-like domain-containing protein. (177 aa)
LOC102364515Uncharacterized protein. (221 aa)
ERBB4-2Protein kinase domain-containing protein. (789 aa)
KITKIT proto-oncogene, receptor tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (937 aa)
GAB2GRB2 associated binding protein 2. (550 aa)
EPGNEpithelial mitogen. (161 aa)
H3A7N7_LATCHGF_recep_IV domain-containing protein. (99 aa)
INSCINSC spindle orientation adaptor protein. (407 aa)
LOC102356182Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (196 aa)
HBEGFHeparin binding EGF like growth factor. (209 aa)
FRS2Fibroblast growth factor receptor substrate 2. (502 aa)
PTPN11Protein tyrosine phosphatase non-receptor type 11. (586 aa)
LOC102350355Uncharacterized protein. (957 aa)
H3ACE0_LATCHInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (111 aa)
FGFR2Fibroblast growth factor receptor. (810 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
LOC102361473Uncharacterized protein. (1211 aa)
PIP5K1APhosphatidylinositol-4-phosphate 5-kinase type 1 alpha. (878 aa)
LOC102348007Phosphoinositide-3-kinase, regulatory subunit 3b (gamma). (392 aa)
AREGAmphiregulin. (235 aa)
PPP2R5BSerine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (495 aa)
GAB1GRB2 associated binding protein 1. (534 aa)
LOC102349237Uncharacterized protein. (153 aa)
PIK3CDPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta; Belongs to the PI3/PI4-kinase family. (1006 aa)
PIK3AP1Phosphoinositide-3-kinase adaptor protein 1. (732 aa)
PDGFRAUncharacterized protein. (1094 aa)
STRN3Striatin 3. (788 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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