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PSMC2 PSMC2 PSME1 PSME1 LOC102346166 LOC102346166 LOC102350907 LOC102350907 PSMB4 PSMB4 H3A4V8_LATCH H3A4V8_LATCH PSMD14 PSMD14 PSMA7 PSMA7 PSMB3 PSMB3 ATM ATM PSMD13 PSMD13 RPS27A RPS27A KXD1 KXD1 PSMF1 PSMF1 MDM2 MDM2 PSMD11 PSMD11 PSMC5 PSMC5 PSMD7 PSMD7 COP1 COP1 PWWP2A PWWP2A PSMA8 PSMA8 PSMD12 PSMD12 PSMA1 PSMA1 LOC102362445 LOC102362445 LOC102349804 LOC102349804 PSMC6 PSMC6 PSMC3 PSMC3 PSMA3 PSMA3 PSMB7 PSMB7 PSMD9 PSMD9 LOC102365446 LOC102365446 PSMA6 PSMA6 MDM4 MDM4 PSMB2 PSMB2 PSMA5 PSMA5 PSMD8 PSMD8 LOC102350961 LOC102350961 LOC102358862 LOC102358862 PSMB11 PSMB11 PSMD3 PSMD3 PSMD5 PSMD5 PSMB9 PSMB9 PSMC1 PSMC1 PSMB8 PSMB8 TP53 TP53 PSMB10 PSMB10 PSMA2 PSMA2 PSMD10 PSMD10 PSMC4 PSMC4 PSMD1 PSMD1 PSMA4 PSMA4 PSME2 PSME2 PSMB6 PSMB6 PSME4 PSME4 PSMD6 PSMD6 PSME3 PSME3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (445 aa)
PSME1Proteasome activator subunit 1. (252 aa)
LOC102346166Ubiquitin-like domain-containing protein. (95 aa)
LOC102350907Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (274 aa)
H3A4V8_LATCHProteasome subunit beta. (260 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (314 aa)
PSMA7Proteasome subunit alpha type. (251 aa)
PSMB3Proteasome subunit beta 3. (159 aa)
ATMATM serine/threonine kinase. (2375 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (378 aa)
RPS27ARibosomal protein S27a. (156 aa)
KXD1Ubiquitin-like domain-containing protein. (231 aa)
PSMF1Proteasome inhibitor subunit 1. (265 aa)
MDM2E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (485 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (422 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (322 aa)
COP1COP1 E3 ubiquitin ligase. (702 aa)
PWWP2APWWP domain containing 2A. (843 aa)
PSMA8Proteasome subunit alpha type. (251 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (455 aa)
PSMA1Proteasome subunit alpha type. (269 aa)
LOC102362445PCI domain-containing protein. (376 aa)
LOC102349804Proteasome subunit alpha type. (274 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (389 aa)
PSMC3Proteasome 26S subunit, ATPase 3. (192 aa)
PSMA3Proteasome subunit alpha type. (259 aa)
PSMB7Proteasome subunit beta 7. (289 aa)
PSMD9Proteasome 26S subunit, non-ATPase 9. (210 aa)
LOC102365446Proteasome subunit alpha type. (246 aa)
PSMA6Proteasome subunit alpha type. (289 aa)
MDM4Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. (491 aa)
PSMB2Proteasome subunit beta. (199 aa)
PSMA5Proteasome subunit alpha type. (244 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (309 aa)
LOC102350961Proteasome subunit beta. (260 aa)
LOC102358862Proteasome subunit beta. (272 aa)
PSMB11Proteasome subunit beta. (269 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (524 aa)
PSMD5Proteasome 26S subunit, non-ATPase 5. (501 aa)
PSMB9Proteasome subunit beta. (219 aa)
PSMC1Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (451 aa)
PSMB8Proteasome subunit beta. (271 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (401 aa)
PSMB10Proteasome subunit beta. (278 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
PSMD10Proteasome 26S subunit, non-ATPase 10. (234 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (316 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (730 aa)
PSMA4Proteasome subunit alpha type. (272 aa)
PSME2Proteasome activator subunit 2. (241 aa)
PSMB6Proteasome subunit beta. (245 aa)
PSME4Proteasome activator subunit 4. (1848 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (389 aa)
PSME3Proteasome activator subunit 3. (257 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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