STRINGSTRING
PSMD10 PSMD10 PSMA1 PSMA1 H3AWT9_LATCH H3AWT9_LATCH CDKN1B CDKN1B MCM9 MCM9 PSMD12 PSMD12 PPP2R1A PPP2R1A ERCC6L2 ERCC6L2 CENPL CENPL ORC1 ORC1 NUDC NUDC PSMA8 PSMA8 H3AU40_LATCH H3AU40_LATCH PWWP2A PWWP2A LOC102346472 LOC102346472 ANAPC1 ANAPC1 H3ATF5_LATCH H3ATF5_LATCH H3ASX0_LATCH H3ASX0_LATCH COP1 COP1 MCM2 MCM2 PIAS4 PIAS4 PSMD7 PSMD7 NSD2 NSD2 RCBTB1 RCBTB1 PSMC5 PSMC5 NUP107 NUP107 ZNF385B ZNF385B RAD17 RAD17 YWHAQ YWHAQ PIEZO1 PIEZO1 H2BE1 H2BE1 PSMD11 PSMD11 H3APN8_LATCH H3APN8_LATCH MDM2 MDM2 ANKRD11 ANKRD11 RFC3 RFC3 ATR ATR CDC7 CDC7 H3AN32_LATCH H3AN32_LATCH BABAM1 BABAM1 RAD9A RAD9A LOC102350821 LOC102350821 NUP43 NUP43 MTUS2 MTUS2 MCM6 MCM6 H3ALL9_LATCH H3ALL9_LATCH PSMC4 PSMC4 CHEK2 CHEK2 H2ZS39_LATCH H2ZS39_LATCH H2ZS42_LATCH H2ZS42_LATCH WEE1 WEE1 CDC16 CDC16 LOC102345107 LOC102345107 PSMD1 PSMD1 ORC4 ORC4 PSMA4 PSMA4 PSME2 PSME2 BUB3 BUB3 SKA1 SKA1 CCNA2 CCNA2 H2ZV93_LATCH H2ZV93_LATCH PSMB6 PSMB6 H2ZVL4_LATCH H2ZVL4_LATCH YWHAZ YWHAZ TDRD3 TDRD3 NUP37 NUP37 H2ZWI5_LATCH H2ZWI5_LATCH MCM10 MCM10 MAPRE2 MAPRE2 PSME4 PSME4 H2ZXF6_LATCH H2ZXF6_LATCH PSMD6 PSMD6 CCNE2 CCNE2 H2ZXS9_LATCH H2ZXS9_LATCH CCNE1 CCNE1 UBE2V2 UBE2V2 LOC102355137 LOC102355137 PSME3 PSME3 CENPM CENPM CCNB2 CCNB2 PSMC2 PSMC2 H2ZZP4_LATCH H2ZZP4_LATCH CDCA7 CDCA7 ERCC6L ERCC6L H2ZZX9_LATCH H2ZZX9_LATCH RNF169 RNF169 DYNC1I1 DYNC1I1 NUP98 NUP98 PSME1 PSME1 H3A0V9_LATCH H3A0V9_LATCH LOC102346166 LOC102346166 ZNF385A ZNF385A SPC25 SPC25 LOC102350907 LOC102350907 H3A2S8_LATCH H3A2S8_LATCH NSL1 NSL1 H3A427_LATCH H3A427_LATCH LOC102361505 LOC102361505 H3A4B2_LATCH H3A4B2_LATCH RCBTB2 RCBTB2 MRE11 MRE11 PLK1 PLK1 PSMB4 PSMB4 H3A4V8_LATCH H3A4V8_LATCH PSMD14 PSMD14 H3A560_LATCH H3A560_LATCH NUP85 NUP85 LOC102345465 LOC102345465 H3A5E7_LATCH H3A5E7_LATCH H4C11 H4C11 H3A5V3_LATCH H3A5V3_LATCH MCM7 MCM7 PSMA7 PSMA7 PSMB3 PSMB3 ATM ATM ANAPC11 ANAPC11 FAM89B FAM89B RPA3 RPA3 H3AKN8_LATCH H3AKN8_LATCH TOP3A TOP3A H3AK44_LATCH H3AK44_LATCH NDEL1 NDEL1 CDKN1A CDKN1A H3AJQ7_LATCH H3AJQ7_LATCH TP53BP1 TP53BP1 H3AIY4_LATCH H3AIY4_LATCH DYNC1I2 DYNC1I2 PSMF1 PSMF1 NBN NBN KXD1 KXD1 H3AH17_LATCH H3AH17_LATCH CENPU CENPU PPP2R5B PPP2R5B ORC3 ORC3 MAPRE1 MAPRE1 LOC102362445 LOC102362445 M3XL87_LATCH M3XL87_LATCH M3XL57_LATCH M3XL57_LATCH CDC20B CDC20B ITGB3BP ITGB3BP CENPO CENPO SKA2 SKA2 MEIOB MEIOB PPP2R5C PPP2R5C M3XK14_LATCH M3XK14_LATCH M3XK07_LATCH M3XK07_LATCH CENPN CENPN PPP2R5D PPP2R5D CDCA8 CDCA8 GTSE1 GTSE1 KIF18A KIF18A CDC26 CDC26 MAD1L1 MAD1L1 CENPF CENPF CLASP1 CLASP1 BARD1 BARD1 PKMYT1 PKMYT1 DYNC1LI1 DYNC1LI1 CENPQ CENPQ CDK1 CDK1 RHNO1 RHNO1 RAD9B RAD9B BUB1 BUB1 M3XGI0_LATCH M3XGI0_LATCH BICRA BICRA LOC102349804 LOC102349804 PSMC6 PSMC6 NUP160 NUP160 MCM3 MCM3 RPS27A RPS27A MAD2L1 MAD2L1 WEE2 WEE2 H3AFK9_LATCH H3AFK9_LATCH CCNA1 CCNA1 SEH1L SEH1L H3AF83_LATCH H3AF83_LATCH H3AF58_LATCH H3AF58_LATCH UBE2N UBE2N RPA1 RPA1 CCNB1 CCNB1 H3AE13_LATCH H3AE13_LATCH KIF2C KIF2C DYNC1LI2 DYNC1LI2 RAD1 RAD1 NDE1 NDE1 RMI2 RMI2 BLM BLM ANKRD12 ANKRD12 CLASP2 CLASP2 H3A8A9_LATCH H3A8A9_LATCH ORC6 ORC6 H3A8L7_LATCH H3A8L7_LATCH CDC20 CDC20 ZNF385C ZNF385C RMI1 RMI1 MCM5 MCM5 ZWILCH ZWILCH YWHAG YWHAG TOPBP1 TOPBP1 BRCA1 BRCA1 HUS1 HUS1 RNF8 RNF8 H3ABS6_LATCH H3ABS6_LATCH PSMD13 PSMD13 UBE2S UBE2S YWHAB YWHAB CDK2 CDK2 PSMC3 PSMC3 PSMA3 PSMA3 ATRIP ATRIP CKAP5 CKAP5 H3BHP0_LATCH H3BHP0_LATCH PPP2R1B PPP2R1B PSMB7 PSMB7 UBE2C UBE2C EXD2 EXD2 RFC2 RFC2 ZW10 ZW10 ANAPC5 ANAPC5 CLIP2 CLIP2 PSMD9 PSMD9 LOC102365446 LOC102365446 DYNLL1 DYNLL1 XPO1 XPO1 MIS12 MIS12 PAFAH1B1 PAFAH1B1 B9D2 B9D2 CLIP1 CLIP1 KNTC1 KNTC1 RFC4 RFC4 H3BEF8_LATCH H3BEF8_LATCH RBBP8 RBBP8 PSMA6 PSMA6 BIRC5 BIRC5 PPP2R5E PPP2R5E SPDL1 SPDL1 ANAPC16 ANAPC16 LOC102367189 LOC102367189 H3BDB3_LATCH H3BDB3_LATCH INCENP INCENP YWHAH YWHAH AHCTF1 AHCTF1 CDC23 CDC23 MDM4 MDM4 EXO1 EXO1 RFC5 RFC5 CLSPN CLSPN CHEK1 CHEK1 CENPI CENPI PPP2CA PPP2CA MCM8 MCM8 KIF18B KIF18B RCC2 RCC2 PSMB2 PSMB2 ANAPC7 ANAPC7 PSMA5 PSMA5 H3B863_LATCH H3B863_LATCH MAPRE3 MAPRE3 PSMD8 PSMD8 SLF1 SLF1 CDC27 CDC27 LOC102350961 LOC102350961 CDC45 CDC45 LOC102358862 LOC102358862 PSMB11 PSMB11 WDR41 WDR41 CENPC CENPC CCNB3 CCNB3 PSMD3 PSMD3 BRCC3 BRCC3 PIEZO2 PIEZO2 PSMD5 PSMD5 ORC2 ORC2 PMF1 PMF1 LOC102365218 LOC102365218 PSMB9 PSMB9 PSMC1 PSMC1 PSMB8 PSMB8 TP53 TP53 H3B1Z1_LATCH H3B1Z1_LATCH ANAPC2 ANAPC2 SEC13 SEC13 MEIOC MEIOC NUP133 NUP133 DYNC1H1 DYNC1H1 PSMB10 PSMB10 CDKN1C CDKN1C MCM4 MCM4 ORC5 ORC5 ANAPC10 ANAPC10 DNA2 DNA2 CENPK CENPK PSMA2 PSMA2 RANGAP1 RANGAP1 DBF4 DBF4 H3AYY3_LATCH H3AYY3_LATCH
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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PSMD10Proteasome 26S subunit, non-ATPase 10. (234 aa)
PSMA1Proteasome subunit alpha type. (269 aa)
H3AWT9_LATCHUncharacterized protein; Belongs to the cyclin family. (271 aa)
CDKN1BCyclin dependent kinase inhibitor 1B. (198 aa)
MCM9Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (1120 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (455 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (591 aa)
ERCC6L2ERCC excision repair 6 like 2. (1527 aa)
CENPLCentromere protein L. (330 aa)
ORC1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (894 aa)
NUDCNuclear distribution C, dynein complex regulator. (337 aa)
PSMA8Proteasome subunit alpha type. (251 aa)
H3AU40_LATCHPiezo-type mechanosensitive ion channel component. (2543 aa)
PWWP2APWWP domain containing 2A. (843 aa)
LOC102346472Uncharacterized protein. (168 aa)
ANAPC1Anaphase promoting complex subunit 1. (1891 aa)
H3ATF5_LATCHCdc6_C domain-containing protein. (525 aa)
H3ASX0_LATCHKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (397 aa)
COP1COP1 E3 ubiquitin ligase. (702 aa)
MCM2DNA helicase; Belongs to the MCM family. (888 aa)
PIAS4Protein inhibitor of activated STAT 4. (370 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (322 aa)
NSD2Nuclear receptor binding SET domain protein 2. (1348 aa)
RCBTB1RCC1 and BTB domain containing protein 1. (531 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
NUP107Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (930 aa)
ZNF385BZinc finger protein 385B. (393 aa)
RAD17RAD17 checkpoint clamp loader component. (748 aa)
YWHAQ14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (154 aa)
PIEZO1Piezo-type mechanosensitive ion channel component. (2125 aa)
H2BE1Histone H2B; Belongs to the histone H2B family. (122 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (422 aa)
H3APN8_LATCHReverse transcriptase domain-containing protein. (202 aa)
MDM2E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (485 aa)
ANKRD11Ankyrin repeat domain 11. (2717 aa)
RFC3Replication factor C subunit 3. (237 aa)
ATRATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2654 aa)
CDC7Cell division cycle 7. (560 aa)
H3AN32_LATCHUncharacterized protein. (3251 aa)
BABAM1BRISC and BRCA1 A complex member 1. (323 aa)
RAD9AUncharacterized protein. (273 aa)
LOC102350821Serine/threonine-protein phosphatase. (309 aa)
NUP43Nucleoporin 43. (374 aa)
MTUS2Uncharacterized protein. (308 aa)
MCM6DNA helicase; Belongs to the MCM family. (826 aa)
H3ALL9_LATCHUncharacterized protein. (251 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (316 aa)
CHEK2Checkpoint kinase 2. (411 aa)
H2ZS39_LATCHHistone H2B; Belongs to the histone H2B family. (135 aa)
H2ZS42_LATCHAAA_23 domain-containing protein. (88 aa)
WEE1WEE1 G2 checkpoint kinase. (382 aa)
CDC16Cell division cycle 16. (545 aa)
LOC102345107Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (181 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (730 aa)
ORC4Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (360 aa)
PSMA4Proteasome subunit alpha type. (272 aa)
PSME2Proteasome activator subunit 2. (241 aa)
BUB3BUB3 mitotic checkpoint protein. (361 aa)
SKA1Spindle and kinetochore associated complex subunit 1. (255 aa)
CCNA2Cyclin A2; Belongs to the cyclin family. (447 aa)
H2ZV93_LATCH14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (117 aa)
PSMB6Proteasome subunit beta. (245 aa)
H2ZVL4_LATCHHistone domain-containing protein; Belongs to the histone H2B family. (90 aa)
YWHAZ14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (244 aa)
TDRD3Tudor domain containing 3. (746 aa)
NUP37Nucleoporin 37. (326 aa)
H2ZWI5_LATCHUncharacterized protein. (1469 aa)
MCM10Minichromosome maintenance 10 replication initiation factor. (878 aa)
MAPRE2Microtubule associated protein RP/EB family member 2. (283 aa)
PSME4Proteasome activator subunit 4. (1848 aa)
H2ZXF6_LATCHUncharacterized protein. (56 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (389 aa)
CCNE2Cyclin E2; Belongs to the cyclin family. (307 aa)
H2ZXS9_LATCHCyclin N-terminal domain-containing protein; Belongs to the cyclin family. (398 aa)
CCNE1Cyclin E1; Belongs to the cyclin family. (417 aa)
UBE2V2Ubiquitin conjugating enzyme E2 V2. (55 aa)
LOC102355137PH domain-containing protein. (525 aa)
PSME3Proteasome activator subunit 3. (257 aa)
CENPMUncharacterized protein. (175 aa)
CCNB2Cyclin B2; Belongs to the cyclin family. (404 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (445 aa)
H2ZZP4_LATCHHistone H2B; Belongs to the histone H2B family. (138 aa)
CDCA7Cell division cycle associated 7. (405 aa)
ERCC6LERCC excision repair 6 like, spindle assembly checkpoint helicase. (1224 aa)
H2ZZX9_LATCHU1-type domain-containing protein. (105 aa)
RNF169Ring finger protein 169. (684 aa)
DYNC1I1Uncharacterized protein. (99 aa)
NUP98Nucleoporin 98. (1790 aa)
PSME1Proteasome activator subunit 1. (252 aa)
H3A0V9_LATCHDUF5595 domain-containing protein. (661 aa)
LOC102346166Ubiquitin-like domain-containing protein. (95 aa)
ZNF385AZinc finger protein 385A. (403 aa)
SPC25SPC25 component of NDC80 kinetochore complex. (232 aa)
LOC102350907Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
H3A2S8_LATCHHistone H2B; Belongs to the histone H2B family. (138 aa)
NSL1Uncharacterized protein. (261 aa)
H3A427_LATCHHistone H2B; Belongs to the histone H2B family. (137 aa)
LOC102361505Histone H2B; Belongs to the histone H2B family. (126 aa)
H3A4B2_LATCHReverse transcriptase domain-containing protein. (787 aa)
RCBTB2RCC1 and BTB domain containing protein 2. (413 aa)
MRE11Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (710 aa)
PLK1Serine/threonine-protein kinase PLK. (595 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (274 aa)
H3A4V8_LATCHProteasome subunit beta. (260 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (314 aa)
H3A560_LATCHRAD50 homolog, double strand break repair protein. (1193 aa)
NUP85Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (656 aa)
LOC102345465Uncharacterized protein. (347 aa)
H3A5E7_LATCHHistone H2B; Belongs to the histone H2B family. (130 aa)
H4C11Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
H3A5V3_LATCHRecQ helicase-like 4. (1456 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (614 aa)
PSMA7Proteasome subunit alpha type. (251 aa)
PSMB3Proteasome subunit beta 3. (159 aa)
ATMATM serine/threonine kinase. (2375 aa)
ANAPC11APC11 anaphase promoting complex subunit 11 homolog (yeast). (84 aa)
FAM89BFamily with sequence similarity 89 member B. (179 aa)
RPA3Replication protein A3. (121 aa)
H3AKN8_LATCHUncharacterized protein. (129 aa)
TOP3ADNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (999 aa)
H3AK44_LATCHHistone domain-containing protein; Belongs to the histone H2B family. (105 aa)
NDEL1NudE neurodevelopment protein 1 like 1. (343 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (171 aa)
H3AJQ7_LATCHUncharacterized protein. (46 aa)
TP53BP1Tumor protein p53 binding protein 1. (2149 aa)
H3AIY4_LATCHUncharacterized protein. (161 aa)
DYNC1I2Dynein cytoplasmic 1 intermediate chain 2. (636 aa)
PSMF1Proteasome inhibitor subunit 1. (265 aa)
NBNNibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (772 aa)
KXD1Ubiquitin-like domain-containing protein. (231 aa)
H3AH17_LATCHShugoshin_C domain-containing protein. (672 aa)
CENPUCentromere protein U. (311 aa)
PPP2R5BSerine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (495 aa)
ORC3Origin recognition complex subunit 3. (720 aa)
MAPRE1Microtubule associated protein RP/EB family member 1. (262 aa)
LOC102362445PCI domain-containing protein. (376 aa)
M3XL87_LATCHUncharacterized protein. (157 aa)
M3XL57_LATCHReverse transcriptase domain-containing protein. (332 aa)
CDC20BCell division cycle 20B. (285 aa)
ITGB3BPUncharacterized protein. (159 aa)
CENPOCentromere protein O. (254 aa)
SKA2Spindle and kinetochore associated complex subunit 2. (249 aa)
MEIOBMeiosis specific with OB-fold. (470 aa)
PPP2R5CSerine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (610 aa)
M3XK14_LATCHUncharacterized protein. (196 aa)
M3XK07_LATCHUncharacterized protein. (251 aa)
CENPNCentromere protein N. (348 aa)
PPP2R5DSerine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (619 aa)
CDCA8Nbl1_Borealin_N domain-containing protein. (289 aa)
GTSE1GTSE1_N domain-containing protein. (721 aa)
KIF18AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (962 aa)
CDC26Cell division cycle 26. (85 aa)
MAD1L1Mitotic arrest deficient 1 like 1. (684 aa)
CENPFCentromere protein F. (3070 aa)
CLASP1Uncharacterized protein. (66 aa)
BARD1BRCA1 associated RING domain 1. (866 aa)
PKMYT1Protein kinase, membrane associated tyrosine/threonine 1. (563 aa)
DYNC1LI1Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (502 aa)
CENPQUncharacterized protein. (155 aa)
CDK1Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (302 aa)
RHNO1RAD9-HUS1-RAD1 interacting nuclear orphan 1. (319 aa)
RAD9BCell cycle checkpoint control protein; Belongs to the rad9 family. (411 aa)
BUB1BUB1 mitotic checkpoint serine/threonine kinase. (1272 aa)
M3XGI0_LATCHUncharacterized protein. (117 aa)
BICRABRD4 interacting chromatin remodeling complex associated protein. (1753 aa)
LOC102349804Proteasome subunit alpha type. (274 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (389 aa)
NUP160Nucleoporin 160. (1326 aa)
MCM3DNA helicase; Belongs to the MCM family. (820 aa)
RPS27ARibosomal protein S27a. (156 aa)
MAD2L1Mitotic arrest deficient 2 like 1. (202 aa)
WEE2Wee1-like protein kinase. (515 aa)
H3AFK9_LATCHRING-type domain-containing protein. (482 aa)
CCNA1Cyclin A1; Belongs to the cyclin family. (433 aa)
SEH1LSEH1 like nucleoporin; Belongs to the WD repeat SEC13 family. (468 aa)
H3AF83_LATCHUncharacterized protein. (869 aa)
H3AF58_LATCHUncharacterized protein. (251 aa)
UBE2NUbiquitin-conjugating enzyme E2Na; Belongs to the ubiquitin-conjugating enzyme family. (159 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (495 aa)
CCNB1Cyclin B1; Belongs to the cyclin family. (404 aa)
H3AE13_LATCHUncharacterized protein. (380 aa)
KIF2CKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (501 aa)
DYNC1LI2Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (505 aa)
RAD1RAD1 checkpoint DNA exonuclease. (281 aa)
NDE1NudE neurodevelopment protein 1. (345 aa)
RMI2RecQ mediated genome instability 2. (158 aa)
BLMBLM RecQ like helicase. (1450 aa)
ANKRD12Ankyrin repeat domain 12. (2105 aa)
CLASP2Cytoplasmic linker associated protein 2. (1303 aa)
H3A8A9_LATCHUncharacterized protein. (271 aa)
ORC6Origin recognition complex subunit 6. (257 aa)
H3A8L7_LATCHUncharacterized protein. (117 aa)
CDC20Cell division cycle 20. (502 aa)
ZNF385CZinc finger protein 385C. (558 aa)
RMI1RecQ mediated genome instability 1. (616 aa)
MCM5DNA helicase; Belongs to the MCM family. (635 aa)
ZWILCHZwilch kinetochore protein. (512 aa)
YWHAGTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma; Belongs to the 14-3-3 family. (247 aa)
TOPBP1DNA topoisomerase II binding protein 1. (1542 aa)
BRCA1BRCA1 DNA repair associated. (1873 aa)
HUS1Checkpoint protein; Belongs to the HUS1 family. (225 aa)
RNF8E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (542 aa)
H3ABS6_LATCHUncharacterized protein. (443 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (378 aa)
UBE2SUbiquitin conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family. (181 aa)
YWHABTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (244 aa)
CDK2Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa)
PSMC3Proteasome 26S subunit, ATPase 3. (192 aa)
PSMA3Proteasome subunit alpha type. (259 aa)
ATRIPATR interacting protein. (782 aa)
CKAP5Cytoskeleton associated protein 5. (1557 aa)
H3BHP0_LATCHUncharacterized protein. (410 aa)
PPP2R1BProtein phosphatase 2 scaffold subunit Abeta. (589 aa)
PSMB7Proteasome subunit beta 7. (289 aa)
UBE2CUbiquitin conjugating enzyme E2 C; Belongs to the ubiquitin-conjugating enzyme family. (179 aa)
EXD2Exonuclease 3'-5' domain containing 2. (617 aa)
RFC2Replication factor C subunit 2. (396 aa)
ZW10Zw10 kinetochore protein. (708 aa)
ANAPC5Anaphase promoting complex subunit 5. (755 aa)
CLIP2CAP-Gly domain containing linker protein 2. (1042 aa)
PSMD9Proteasome 26S subunit, non-ATPase 9. (210 aa)
LOC102365446Proteasome subunit alpha type. (246 aa)
DYNLL1Dynein light chain. (115 aa)
XPO1Exportin 1. (1078 aa)
MIS12MIS12 kinetochore complex component. (215 aa)
PAFAH1B1Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family. (410 aa)
B9D2B9 domain containing 2. (175 aa)
CLIP1CAP-Gly domain containing linker protein 1. (1445 aa)
KNTC1Kinetochore associated 1. (2225 aa)
RFC4Replication factor C subunit 4. (360 aa)
H3BEF8_LATCHCytoplasmic linker associated protein 1a. (1413 aa)
RBBP8RB binding protein 8, endonuclease. (906 aa)
PSMA6Proteasome subunit alpha type. (289 aa)
BIRC5Baculoviral IAP repeat containing 5. (139 aa)
PPP2R5ESerine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (467 aa)
SPDL1Protein Spindly; Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex; Belongs to the Spindly family. (614 aa)
ANAPC16Anaphase promoting complex subunit 16. (119 aa)
LOC102367189Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (342 aa)
H3BDB3_LATCHUncharacterized protein. (402 aa)
INCENPINCENP_ARK-bind domain-containing protein. (887 aa)
YWHAHTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta; Belongs to the 14-3-3 family. (247 aa)
AHCTF1AT-hook containing transcription factor 1. (2245 aa)
CDC23Cell division cycle 23. (581 aa)
MDM4Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. (491 aa)
EXO1Exonuclease 1. (805 aa)
RFC5Replication factor C subunit 5. (333 aa)
CLSPNClaspin. (1326 aa)
CHEK1Checkpoint kinase 1; Belongs to the protein kinase superfamily. (475 aa)
CENPICentromere protein I. (701 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
MCM8Minichromosome maintenance 8 homologous recombination repair factor; Belongs to the MCM family. (852 aa)
KIF18BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (645 aa)
RCC2Regulator of chromosome condensation 2. (498 aa)
PSMB2Proteasome subunit beta. (199 aa)
ANAPC7Anaphase promoting complex subunit 7. (565 aa)
PSMA5Proteasome subunit alpha type. (244 aa)
H3B863_LATCHU1-type domain-containing protein. (114 aa)
MAPRE3Microtubule associated protein RP/EB family member 3. (305 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (309 aa)
SLF1SMC5-SMC6 complex localization factor 1. (1063 aa)
CDC27Cell division cycle 27. (833 aa)
LOC102350961Proteasome subunit beta. (260 aa)
CDC45Cell division cycle 45. (609 aa)
LOC102358862Proteasome subunit beta. (272 aa)
PSMB11Proteasome subunit beta. (269 aa)
WDR41WD repeat domain 41. (456 aa)
CENPCCENP-C_C domain-containing protein. (824 aa)
CCNB3Cyclin B3; Belongs to the cyclin family. (416 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (524 aa)
BRCC3BRCA1/BRCA2-containing complex subunit 3. (291 aa)
PIEZO2Piezo-type mechanosensitive ion channel component. (2426 aa)
PSMD5Proteasome 26S subunit, non-ATPase 5. (501 aa)
ORC2Origin recognition complex subunit 2. (568 aa)
PMF1Polyamine modulated factor 1. (223 aa)
LOC102365218Uncharacterized protein. (210 aa)
PSMB9Proteasome subunit beta. (219 aa)
PSMC1Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (451 aa)
PSMB8Proteasome subunit beta. (271 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (401 aa)
H3B1Z1_LATCHUncharacterized protein. (352 aa)
ANAPC2Anaphase promoting complex subunit 2; Belongs to the cullin family. (816 aa)
SEC13SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family. (320 aa)
MEIOCMeiosis specific with coiled-coil domain. (938 aa)
NUP133Nucleoporin 133; Belongs to the actin family. (1421 aa)
DYNC1H1Dynein cytoplasmic 1 heavy chain 1. (4615 aa)
PSMB10Proteasome subunit beta. (278 aa)
CDKN1CUncharacterized protein. (215 aa)
MCM4DNA helicase; Belongs to the MCM family. (858 aa)
ORC5Origin recognition complex subunit 5. (264 aa)
ANAPC10Anaphase promoting complex subunit 10. (147 aa)
DNA2DNA replication helicase/nuclease 2. (925 aa)
CENPKCentromere protein K. (291 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
RANGAP1Ran GTPase activating protein 1. (615 aa)
DBF4DBF4 zinc finger. (672 aa)
H3AYY3_LATCHUncharacterized protein. (223 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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