STRINGSTRING
LOC102364341 LOC102364341 GAB1 GAB1 CRK CRK RAP1B RAP1B CRKL CRKL MET MET RAPGEF1 RAPGEF1 RAP1A RAP1A HGF HGF GRB2 GRB2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC102364341Uncharacterized protein. (271 aa)
GAB1GRB2 associated binding protein 1. (534 aa)
CRKCRK proto-oncogene, adaptor protein. (310 aa)
RAP1BRAP1B, member of RAS oncogene family. (184 aa)
CRKLCRK like proto-oncogene, adaptor protein. (219 aa)
METMET proto-oncogene, receptor tyrosine kinase. (1385 aa)
RAPGEF1Rap guanine nucleotide exchange factor 1. (1217 aa)
RAP1ARAP1A, member of RAS oncogene family b. (185 aa)
HGFHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (720 aa)
GRB2Growth factor receptor bound protein 2. (292 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.