10 items (Latimeria chalumnae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC102362571	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (311 aa)
	LOC102365706	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (305 aa)
	CYB5R4	Cytochrome b5 reductase 4. (519 aa)
	OXNAD1	Oxidoreductase NAD binding domain containing 1. (315 aa)
	MTRR	5-methyltetrahydrofolate-homocysteine methyltransferase reductase. (720 aa)
	NOS1	Nitric oxide synthase 1. (1476 aa)
	CYB5RL	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (312 aa)
	POR	NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (676 aa)
	NOS2	Nitric oxide synthase; Produces nitric oxide (NO). (1126 aa)
	NDOR1	NADPH-dependent diflavin oxidoreductase 1; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe/S cluster of CIAPIN1. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (597 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CYB5R4	CYB5RL	ENSLACP00000012728	ENSLACP00000005720	Cytochrome b5 reductase 4.	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	0.584
CYB5R4	LOC102362571	ENSLACP00000012728	ENSLACP00000019213	Cytochrome b5 reductase 4.	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	0.559
CYB5R4	LOC102365706	ENSLACP00000012728	ENSLACP00000013261	Cytochrome b5 reductase 4.	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	0.559
CYB5R4	MTRR	ENSLACP00000012728	ENSLACP00000008467	Cytochrome b5 reductase 4.	5-methyltetrahydrofolate-homocysteine methyltransferase reductase.	0.622
CYB5R4	NDOR1	ENSLACP00000012728	ENSLACP00000015089	Cytochrome b5 reductase 4.	NADPH-dependent diflavin oxidoreductase 1; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe/S cluster of CIAPIN1. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	0.622
CYB5R4	NOS1	ENSLACP00000012728	ENSLACP00000007966	Cytochrome b5 reductase 4.	Nitric oxide synthase 1.	0.622
CYB5R4	NOS2	ENSLACP00000012728	ENSLACP00000020145	Cytochrome b5 reductase 4.	Nitric oxide synthase; Produces nitric oxide (NO).	0.622
CYB5R4	OXNAD1	ENSLACP00000012728	ENSLACP00000009365	Cytochrome b5 reductase 4.	Oxidoreductase NAD binding domain containing 1.	0.559
CYB5R4	POR	ENSLACP00000012728	ENSLACP00000021070	Cytochrome b5 reductase 4.	NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	0.622
CYB5RL	CYB5R4	ENSLACP00000005720	ENSLACP00000012728	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	Cytochrome b5 reductase 4.	0.584
CYB5RL	POR	ENSLACP00000005720	ENSLACP00000021070	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	0.498
LOC102362571	CYB5R4	ENSLACP00000019213	ENSLACP00000012728	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	Cytochrome b5 reductase 4.	0.559
LOC102362571	POR	ENSLACP00000019213	ENSLACP00000021070	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	0.496
LOC102365706	CYB5R4	ENSLACP00000013261	ENSLACP00000012728	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	Cytochrome b5 reductase 4.	0.559
LOC102365706	POR	ENSLACP00000013261	ENSLACP00000021070	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	0.496
MTRR	CYB5R4	ENSLACP00000008467	ENSLACP00000012728	5-methyltetrahydrofolate-homocysteine methyltransferase reductase.	Cytochrome b5 reductase 4.	0.622
NDOR1	CYB5R4	ENSLACP00000015089	ENSLACP00000012728	NADPH-dependent diflavin oxidoreductase 1; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe/S cluster of CIAPIN1. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	Cytochrome b5 reductase 4.	0.622
NOS1	CYB5R4	ENSLACP00000007966	ENSLACP00000012728	Nitric oxide synthase 1.	Cytochrome b5 reductase 4.	0.622
NOS1	NOS2	ENSLACP00000007966	ENSLACP00000020145	Nitric oxide synthase 1.	Nitric oxide synthase; Produces nitric oxide (NO).	0.902
NOS2	CYB5R4	ENSLACP00000020145	ENSLACP00000012728	Nitric oxide synthase; Produces nitric oxide (NO).	Cytochrome b5 reductase 4.	0.622