STRINGSTRING
LOC102354872 LOC102354872 H2ZTV4_LATCH H2ZTV4_LATCH NALCN NALCN H2ZUL4_LATCH H2ZUL4_LATCH TRPV4 TRPV4 HCN4 HCN4 TRPC4 TRPC4 H3A0G5_LATCH H3A0G5_LATCH SCN10A SCN10A ITPR1 ITPR1 PKD1 PKD1 CNGA4 CNGA4 PKD2 PKD2 TRPM5 TRPM5 H3A6P6_LATCH H3A6P6_LATCH CACNA1B CACNA1B TRPV6 TRPV6 CATSPER3 CATSPER3 LOC102354655 LOC102354655 CNGA1 CNGA1 KCNQ2 KCNQ2 CACNA1F CACNA1F CACNA1G CACNA1G H3AFD4_LATCH H3AFD4_LATCH SCN2A SCN2A H3AG91_LATCH H3AG91_LATCH H3AGJ3_LATCH H3AGJ3_LATCH CACNA1I CACNA1I TPTE2 TPTE2 CNGB3 CNGB3 TRPM6 TRPM6 H3AMJ0_LATCH H3AMJ0_LATCH SCN4A SCN4A H3AQD6_LATCH H3AQD6_LATCH TPCN1 TPCN1 RYR3 RYR3 CACNA1A CACNA1A CACNA1D CACNA1D TRPC1 TRPC1 RYR2 RYR2 CACNA1E CACNA1E H3AW07_LATCH H3AW07_LATCH HCN2 HCN2 LOC102362869 LOC102362869 TRPA1 TRPA1 CATSPER2 CATSPER2 H3AZ90_LATCH H3AZ90_LATCH KCND2-2 KCND2-2 PKD2L2 PKD2L2 TRPM2 TRPM2 CNGA3 CNGA3 LOC102347888 LOC102347888 CNGA2 CNGA2 TRPM4 TRPM4 H3B4Z8_LATCH H3B4Z8_LATCH KCND2 KCND2 H3B6R7_LATCH H3B6R7_LATCH ITPR3 ITPR3 CACNA1C CACNA1C KCNB1 KCNB1 LOC102347960 LOC102347960 PKD2L1 PKD2L1 CACNA1S CACNA1S H3BDW1_LATCH H3BDW1_LATCH TRPM7 TRPM7 TRPM1 TRPM1 KCND3 KCND3 H3BGI5_LATCH H3BGI5_LATCH RYR1 RYR1 H3BH83_LATCH H3BH83_LATCH SCN8A SCN8A M3XL44_LATCH M3XL44_LATCH
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC102354872Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1673 aa)
H2ZTV4_LATCHIon_trans domain-containing protein. (103 aa)
NALCNSodium leak channel, non-selective. (1590 aa)
H2ZUL4_LATCHUncharacterized protein. (1374 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (870 aa)
HCN4Hyperpolarization activated cyclic nucleotide gated potassium channel 4. (1184 aa)
TRPC4Transient receptor potential cation channel subfamily C member 4; Belongs to the transient receptor (TC 1.A.4) family. (760 aa)
H3A0G5_LATCHUncharacterized protein. (2422 aa)
SCN10ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1202 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2725 aa)
PKD1Polycystin 1, transient receptor potential channel interacting. (4241 aa)
CNGA4Cyclic nucleotide gated channel subunit alpha 4. (533 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (890 aa)
TRPM5Transient receptor potential cation channel subfamily M member 5. (1109 aa)
H3A6P6_LATCHANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (593 aa)
CACNA1BVoltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2026 aa)
TRPV6Transient receptor potential cation channel subfamily V member 6; Belongs to the transient receptor (TC 1.A.4) family. (538 aa)
CATSPER3Cation channel sperm associated 3. (334 aa)
LOC102354655ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (600 aa)
CNGA1Cyclic nucleotide gated channel subunit alpha 1. (542 aa)
KCNQ2Potassium voltage-gated channel subfamily Q member 2; Belongs to the potassium channel family. (876 aa)
CACNA1FCalcium voltage-gated channel subunit alpha1 F. (1657 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2282 aa)
H3AFD4_LATCHCyclic nucleotide-binding domain-containing protein. (486 aa)
SCN2ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1702 aa)
H3AG91_LATCHUncharacterized protein. (537 aa)
H3AGJ3_LATCHTransient receptor potential cation channel, subfamily M, member 3. (1326 aa)
CACNA1IVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (1831 aa)
TPTE2Transmembrane phosphatase with tensin homology. (511 aa)
CNGB3Cyclic nucleotide gated channel subunit beta 3. (449 aa)
TRPM6Transient receptor potential cation channel subfamily M member 6. (1930 aa)
H3AMJ0_LATCHIon_trans domain-containing protein. (734 aa)
SCN4ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1836 aa)
H3AQD6_LATCHIon_trans domain-containing protein. (143 aa)
TPCN1Two pore segment channel 1. (708 aa)
RYR3Uncharacterized protein. (3558 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (1963 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2025 aa)
TRPC1Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (793 aa)
RYR2Ryanodine receptor 2b (cardiac). (3465 aa)
CACNA1EVoltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. (1734 aa)
H3AW07_LATCHIon_trans domain-containing protein. (308 aa)
HCN2Hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2. (946 aa)
LOC102362869ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (559 aa)
TRPA1Transient receptor potential cation channel subfamily A member 1; Belongs to the transient receptor (TC 1.A.4) family. (1138 aa)
CATSPER2Cation channel sperm associated 2. (460 aa)
H3AZ90_LATCHANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (586 aa)
KCND2-2Uncharacterized protein; Belongs to the potassium channel family. (260 aa)
PKD2L2Polycystin 2 like 2, transient receptor potential cation channel. (589 aa)
TRPM2Transient receptor potential cation channel subfamily M member 2. (1473 aa)
CNGA3Cyclic nucleotide gated channel subunit alpha 3. (662 aa)
LOC102347888Cyclic nucleotide-binding domain-containing protein. (513 aa)
CNGA2Cyclic nucleotide gated channel subunit alpha 2. (745 aa)
TRPM4Transient receptor potential cation channel subfamily M member 4. (1178 aa)
H3B4Z8_LATCHRCK N-terminal domain-containing protein. (206 aa)
KCND2Potassium voltage-gated channel subfamily D member 2; Belongs to the potassium channel family. (371 aa)
H3B6R7_LATCHIon_trans domain-containing protein. (303 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2675 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2064 aa)
KCNB1Potassium voltage-gated channel, Shab-related subfamily, member 1; Belongs to the potassium channel family. (677 aa)
LOC102347960Two pore segment channel 3. (743 aa)
PKD2L1Polycystin 2 like 1, transient receptor potential cation channel. (741 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1866 aa)
H3BDW1_LATCHIon_trans domain-containing protein. (364 aa)
TRPM7Transient receptor potential cation channel subfamily M member 7. (1887 aa)
TRPM1Transient receptor potential cation channel subfamily M member 1. (1235 aa)
KCND3BTB domain-containing protein; Belongs to the potassium channel family. (320 aa)
H3BGI5_LATCHUncharacterized protein; Belongs to the potassium channel family. (271 aa)
RYR1Ryanodine receptor 1. (5024 aa)
H3BH83_LATCHCyclic nucleotide-binding domain-containing protein. (1075 aa)
SCN8ASodium voltage-gated channel alpha subunit 8. (1587 aa)
M3XL44_LATCHIon_trans domain-containing protein. (134 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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