STRINGSTRING
HOXD12 HOXD12 FGF7 FGF7 FGF5 FGF5 FGF14 FGF14 FGF2 FGF2 FGF12 FGF12 HOXA10 HOXA10 HOXA13 HOXA13 FGF6 FGF6 FGF18 FGF18 FGF1 FGF1 FGF20 FGF20 FGF19 FGF19 FGF4 FGF4 FGF3 FGF3 FGF13 FGF13 GAPDH GAPDH FGF22 FGF22 FGF16 FGF16 HOXD9 HOXD9 HOXD4 HOXD4 FGF11 FGF11 FGF8 FGF8 MEIS1 MEIS1 LOC102356182 LOC102356182 HAND2 HAND2 IHH IHH GLI3 GLI3 H3A2B0_LATCH H3A2B0_LATCH PBX2 PBX2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HOXD12Homeobox D12. (268 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
FGF5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
FGF14Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (163 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
FGF12Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (243 aa)
HOXA10Homeobox A10. (557 aa)
HOXA13Homeobox A13b. (295 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
FGF19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (217 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (195 aa)
FGF3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (237 aa)
FGF13Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (255 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (359 aa)
FGF22Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (99 aa)
FGF16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
HOXD9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (268 aa)
HOXD4Homeobox D4a. (251 aa)
FGF11Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (246 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
MEIS1Meis homeobox 1. (466 aa)
LOC102356182Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (196 aa)
HAND2Heart and neural crest derivatives expressed 2. (210 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (410 aa)
GLI3GLI family zinc finger 3. (1456 aa)
H3A2B0_LATCHFibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
PBX2Homeobox domain-containing protein. (269 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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