(5 nodes) (2010) Long-term effects of calorie restriction on serum sex-hormone concentrations in men. network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	H3ACE0_LATCH	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (111 aa)
	IL6	Uncharacterized protein. (149 aa)
	LOC102346019	C1q domain-containing protein. (226 aa)
	SHBG	LAM_G_DOMAIN domain-containing protein. (419 aa)
	ADIPOQ	Adiponectin, C1Q and collagen domain containing. (259 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADIPOQ	H3ACE0_LATCH	ENSLACP00000000452	ENSLACP00000007311	Adiponectin, C1Q and collagen domain containing.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.830
ADIPOQ	IL6	ENSLACP00000000452	ENSLACP00000009318	Adiponectin, C1Q and collagen domain containing.	Uncharacterized protein.	0.767
ADIPOQ	LOC102346019	ENSLACP00000000452	ENSLACP00000019134	Adiponectin, C1Q and collagen domain containing.	C1q domain-containing protein.	0.904
ADIPOQ	SHBG	ENSLACP00000000452	ENSLACP00000022326	Adiponectin, C1Q and collagen domain containing.	LAM_G_DOMAIN domain-containing protein.	0.549
H3ACE0_LATCH	ADIPOQ	ENSLACP00000007311	ENSLACP00000000452	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Adiponectin, C1Q and collagen domain containing.	0.830
H3ACE0_LATCH	IL6	ENSLACP00000007311	ENSLACP00000009318	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Uncharacterized protein.	0.773
H3ACE0_LATCH	LOC102346019	ENSLACP00000007311	ENSLACP00000019134	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	C1q domain-containing protein.	0.765
H3ACE0_LATCH	SHBG	ENSLACP00000007311	ENSLACP00000022326	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	LAM_G_DOMAIN domain-containing protein.	0.590
IL6	ADIPOQ	ENSLACP00000009318	ENSLACP00000000452	Uncharacterized protein.	Adiponectin, C1Q and collagen domain containing.	0.767
IL6	H3ACE0_LATCH	ENSLACP00000009318	ENSLACP00000007311	Uncharacterized protein.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.773
IL6	LOC102346019	ENSLACP00000009318	ENSLACP00000019134	Uncharacterized protein.	C1q domain-containing protein.	0.729
LOC102346019	ADIPOQ	ENSLACP00000019134	ENSLACP00000000452	C1q domain-containing protein.	Adiponectin, C1Q and collagen domain containing.	0.904
LOC102346019	H3ACE0_LATCH	ENSLACP00000019134	ENSLACP00000007311	C1q domain-containing protein.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.765
LOC102346019	IL6	ENSLACP00000019134	ENSLACP00000009318	C1q domain-containing protein.	Uncharacterized protein.	0.729
LOC102346019	SHBG	ENSLACP00000019134	ENSLACP00000022326	C1q domain-containing protein.	LAM_G_DOMAIN domain-containing protein.	0.463
SHBG	ADIPOQ	ENSLACP00000022326	ENSLACP00000000452	LAM_G_DOMAIN domain-containing protein.	Adiponectin, C1Q and collagen domain containing.	0.549
SHBG	H3ACE0_LATCH	ENSLACP00000022326	ENSLACP00000007311	LAM_G_DOMAIN domain-containing protein.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.590
SHBG	LOC102346019	ENSLACP00000022326	ENSLACP00000019134	LAM_G_DOMAIN domain-containing protein.	C1q domain-containing protein.	0.463