STRINGSTRING
MCM4 MCM4 TCF7L2-2 TCF7L2-2 MSH6 MSH6 TCF7L2 TCF7L2 LOC102350793 LOC102350793 SKP1 SKP1 KRAS KRAS GLB1L2 GLB1L2 CDX2 CDX2 FOXJ1 FOXJ1 DHFR DHFR CDC34 CDC34 KDM6A KDM6A BRCA1 BRCA1 PTEN PTEN FOXD1 FOXD1 LEF1 LEF1 ATM ATM MSH3 MSH3 NPAT NPAT FOXF2 FOXF2 FOXA2 FOXA2 CDC37 CDC37 SHH SHH LOC102357450 LOC102357450 FOXA1 FOXA1 GLB1L GLB1L
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MCM4DNA helicase; Belongs to the MCM family. (858 aa)
TCF7L2-2Transcription factor 7 like 2. (180 aa)
MSH6DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1361 aa)
TCF7L2Transcription factor 7 like 2. (439 aa)
LOC102350793Beta-galactosidase. (627 aa)
SKP1S-phase kinase associated protein 1; Belongs to the SKP1 family. (172 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
GLB1L2Beta-galactosidase. (639 aa)
CDX2Caudal type homeobox 2. (258 aa)
FOXJ1Forkhead box J1. (452 aa)
DHFRDihydrofolate reductase. (206 aa)
CDC34Cell division cycle 34 homolog (S. cerevisiae) a; Belongs to the ubiquitin-conjugating enzyme family. (241 aa)
KDM6ALysine (K)-specific demethylase 6A. (1452 aa)
BRCA1BRCA1 DNA repair associated. (1873 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (404 aa)
FOXD1Forkhead box D1. (328 aa)
LEF1Lymphoid enhancer binding factor 1. (397 aa)
ATMATM serine/threonine kinase. (2375 aa)
MSH3MutS homolog 3; Component of the post-replicative DNA mismatch repair system (MMR). (798 aa)
NPATNuclear protein, coactivator of histone transcription. (1481 aa)
FOXF2Forkhead box F2a. (379 aa)
FOXA2Forkhead box A2. (429 aa)
CDC37Cell division cycle 37. (382 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (421 aa)
LOC102357450Uncharacterized protein; Belongs to the heat shock protein 70 family. (641 aa)
FOXA1Forkhead box A1. (439 aa)
GLB1LGalactosidase beta 1 like; Belongs to the glycosyl hydrolase 35 family. (636 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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