(23 nodes) (2010) Dermoskeleton morphogenesis in zebrafish fins. network (Latimeria chalumnae)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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Predicted Interactions

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Your Input:
	CHRD	Chordin; Belongs to the chordin family. (948 aa)
	TBX5	T-box transcription factor 5. (522 aa)
	IHH	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (410 aa)
	HAND2	Heart and neural crest derivatives expressed 2. (210 aa)
	WNT7A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
	FGF8	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
	HOXD11	Homeobox D11. (294 aa)
	HOXD12	Homeobox D12. (268 aa)
	EVX2	Even-skipped homeobox 2. (427 aa)
	SHH	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (421 aa)
	ALDH1A2	Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family. (497 aa)
	LOC102357450	Uncharacterized protein; Belongs to the heat shock protein 70 family. (641 aa)
	SPRY4	Sprouty RTK signaling antagonist 4. (282 aa)
	FGF4	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (195 aa)
	FGFR1	Fibroblast growth factor receptor. (824 aa)
	ANGPTL2	Angiopoietin like 2. (498 aa)
	HOXC6	Homeobox C6. (233 aa)
	WNT10A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (387 aa)
	HOXA9	Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (261 aa)
	HOXA10	Homeobox A10. (557 aa)
	HOXA13	Homeobox A13b. (295 aa)
	EVX1	Even-skipped homeobox 1. (383 aa)
	WNT5B	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (378 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANGPTL2	EVX1	ENSLACP00000016321	ENSLACP00000019947	Angiopoietin like 2.	Even-skipped homeobox 1.	0.409
CHRD	FGF4	ENSLACP00000000821	ENSLACP00000014225	Chordin; Belongs to the chordin family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.469
CHRD	FGF8	ENSLACP00000000821	ENSLACP00000007843	Chordin; Belongs to the chordin family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.638
CHRD	IHH	ENSLACP00000000821	ENSLACP00000004851	Chordin; Belongs to the chordin family.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.424
CHRD	SHH	ENSLACP00000000821	ENSLACP00000013019	Chordin; Belongs to the chordin family.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.424
EVX1	ANGPTL2	ENSLACP00000019947	ENSLACP00000016321	Even-skipped homeobox 1.	Angiopoietin like 2.	0.409
FGF4	CHRD	ENSLACP00000014225	ENSLACP00000000821	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Chordin; Belongs to the chordin family.	0.469
FGF4	FGF8	ENSLACP00000014225	ENSLACP00000007843	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.724
FGF4	FGFR1	ENSLACP00000014225	ENSLACP00000015392	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor receptor.	0.829
FGF4	HAND2	ENSLACP00000014225	ENSLACP00000004871	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Heart and neural crest derivatives expressed 2.	0.443
FGF4	IHH	ENSLACP00000014225	ENSLACP00000004851	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.664
FGF4	SHH	ENSLACP00000014225	ENSLACP00000013019	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.664
FGF8	CHRD	ENSLACP00000007843	ENSLACP00000000821	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Chordin; Belongs to the chordin family.	0.638
FGF8	FGF4	ENSLACP00000007843	ENSLACP00000014225	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.724
FGF8	FGFR1	ENSLACP00000007843	ENSLACP00000015392	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor receptor.	0.939
FGF8	HAND2	ENSLACP00000007843	ENSLACP00000004871	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Heart and neural crest derivatives expressed 2.	0.606
FGF8	HOXA13	ENSLACP00000007843	ENSLACP00000019815	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Homeobox A13b.	0.449
FGF8	IHH	ENSLACP00000007843	ENSLACP00000004851	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.745
FGF8	SHH	ENSLACP00000007843	ENSLACP00000013019	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.784
FGF8	SPRY4	ENSLACP00000007843	ENSLACP00000014119	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Sprouty RTK signaling antagonist 4.	0.570