STRINGSTRING
PGD PGD HPGD HPGD LCAT LCAT ALDOB ALDOB G6PD G6PD PLG PLG IDI1 IDI1 PSMA4 PSMA4 F10 F10 F7 F7 PSMC2 PSMC2 NDUFV2 NDUFV2 AADAT AADAT HSD17B4 HSD17B4 NDUFB6 NDUFB6 MRPL48 MRPL48 UQCRB UQCRB NDUFS6 NDUFS6 GMPR2 GMPR2 EIF4G1 EIF4G1 CYB5RL CYB5RL CCT2 CCT2 ANGPTL3 ANGPTL3 GMPR GMPR FGG FGG UBE2N UBE2N IDH3G IDH3G GMPS GMPS FGB FGB PTGS2 PTGS2 FABP7 FABP7 MRPL34 MRPL34 NT5E NT5E HMGCR HMGCR ALDOA ALDOA MRPS14 MRPS14 UBE2A UBE2A TLN1 TLN1 FBP1 FBP1 DCK DCK ATP5MF ATP5MF RPS18 RPS18 NDUFS4 NDUFS4 LOC102365706 LOC102365706 MRPL30 MRPL30 PTGES2 PTGES2 PTPRF PTPRF LOC102352213 LOC102352213 IDH1 IDH1 HPGD-2 HPGD-2 NDUFB4 NDUFB4 PROC PROC RARS1 RARS1 SERPINC1 SERPINC1 SDHB SDHB LOC102362571 LOC102362571 MASP2 MASP2 ITGB2 ITGB2 AGPAT3 AGPAT3 IDH2 IDH2 PTGES3 PTGES3 PSMB7 PSMB7 F2 F2 UBE2G1 UBE2G1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PGD6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (483 aa)
HPGD15-hydroxyprostaglandin dehydrogenase. (165 aa)
LCATLecithin-cholesterol acyltransferase. (428 aa)
ALDOBFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
G6PDGlucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (430 aa)
PLGPlasminogen; Belongs to the peptidase S1 family. Plasminogen subfamily. (725 aa)
IDI1Isopentenyl-diphosphate delta isomerase 1. (278 aa)
PSMA4Proteasome subunit alpha type. (272 aa)
F10Coagulation factor X. (475 aa)
F7Coagulation factor VII. (439 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (445 aa)
NDUFV2NADH:ubiquinone oxidoreductase core subunit V2. (231 aa)
AADATAminoadipate aminotransferase. (425 aa)
HSD17B4Hydroxysteroid 17-beta dehydrogenase 4. (740 aa)
NDUFB6NADH:ubiquinone oxidoreductase subunit B6. (129 aa)
MRPL48Mitochondrial ribosomal protein L48. (212 aa)
UQCRBCytochrome b-c1 complex subunit 7; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain; Belongs to the UQCRB/QCR7 family. (117 aa)
NDUFS6NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (128 aa)
GMPR2GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (350 aa)
EIF4G1Eukaryotic translation initiation factor 4 gamma 1. (1640 aa)
CYB5RLNADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (312 aa)
CCT2Chaperonin containing TCP1 subunit 2. (535 aa)
ANGPTL3Angiopoietin like 3. (454 aa)
GMPRGMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (345 aa)
FGGFibrinogen gamma chain. (376 aa)
UBE2NUbiquitin-conjugating enzyme E2Na; Belongs to the ubiquitin-conjugating enzyme family. (159 aa)
IDH3GIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (400 aa)
GMPSGuanine monophosphate synthase. (683 aa)
FGBFibrinogen beta chain. (454 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (620 aa)
FABP7Fatty acid binding protein 7; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa)
MRPL34Mitochondrial ribosomal protein L34. (134 aa)
NT5E5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. (469 aa)
HMGCR3-hydroxy-3-methylglutaryl coenzyme A reductase. (882 aa)
ALDOAFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
MRPS14Mitochondrial ribosomal protein S14. (143 aa)
UBE2AUbiquitin conjugating enzyme E2 A; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
TLN1Talin 1. (2546 aa)
FBP1Fructose-bisphosphatase 1; Belongs to the FBPase class 1 family. (338 aa)
DCKDeoxycytidine kinase. (263 aa)
ATP5MFUncharacterized protein. (89 aa)
RPS18Ribosomal protein S18; Belongs to the universal ribosomal protein uS13 family. (128 aa)
NDUFS4NADH:ubiquinone oxidoreductase subunit S4. (169 aa)
LOC102365706NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (305 aa)
MRPL30Mitochondrial ribosomal protein L30. (160 aa)
PTGES2Prostaglandin E synthase 2; Belongs to the GST superfamily. (384 aa)
PTPRFUncharacterized protein. (1693 aa)
LOC102352213Ribosomal protein, large, P1; Belongs to the eukaryotic ribosomal protein P1/P2 family. (112 aa)
IDH1Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (414 aa)
HPGD-2Uncharacterized protein. (86 aa)
NDUFB4NADH:ubiquinone oxidoreductase subunit B4. (128 aa)
PROCUncharacterized protein. (444 aa)
RARS1Arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (660 aa)
SERPINC1Serpin family C member 1; Belongs to the serpin family. (485 aa)
SDHBSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (285 aa)
LOC102362571NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (311 aa)
MASP2Mannan binding lectin serine peptidase 2; Belongs to the peptidase S1 family. (557 aa)
ITGB2Integrin beta. (776 aa)
AGPAT31-acylglycerol-3-phosphate O-acyltransferase 3. (380 aa)
IDH2Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (402 aa)
PTGES3Prostaglandin E synthase 3. (161 aa)
PSMB7Proteasome subunit beta 7. (289 aa)
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (618 aa)
UBE2G1Ubiquitin conjugating enzyme E2 G1; Belongs to the ubiquitin-conjugating enzyme family. (170 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: medium (42%) [HD]