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TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (401 aa) | ||||
STAT3 | Signal transducer and activator of transcription. (763 aa) | ||||
JAK1 | Janus kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (613 aa) | ||||
JAK2 | Tyrosine-protein kinase. (1152 aa) | ||||
GAPDHS | Glyceraldehyde-3-phosphate dehydrogenase. (396 aa) | ||||
MYO7A | Myosin VIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2185 aa) | ||||
POU4F3 | POU domain protein. (337 aa) | ||||
GAPDH | Glyceraldehyde-3-phosphate dehydrogenase. (359 aa) |