STRINGSTRING
BRAF BRAF ADAM10 ADAM10 DROSHA DROSHA EPO EPO LOC102348541 LOC102348541 IDO2 IDO2 PTEN PTEN SPARC SPARC ERBB2 ERBB2 CCR7 CCR7 CLDN2 CLDN2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BRAFB-Raf proto-oncogene, serine/threonine kinase. (768 aa)
ADAM10ADAM metallopeptidase domain 10b. (679 aa)
DROSHADrosha ribonuclease III. (1347 aa)
EPOErythropoietin. (179 aa)
LOC102348541Chemokine (C-X-C motif) receptor 1; Belongs to the G-protein coupled receptor 1 family. (353 aa)
IDO2Indoleamine 2,3-dioxygenase 1. (425 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (404 aa)
SPARCSecreted protein acidic and cysteine rich. (304 aa)
ERBB2Receptor protein-tyrosine kinase. (1250 aa)
CCR7C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (379 aa)
CLDN2Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (238 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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