(7 nodes) (2013) Morphological and molecular characterization of dietary-induced pseudo-albinism during post-embryonic development of Solea senegalensis (Kaup, 1858). network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SLC25A5	Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
	TYR	Tyrosinase. (532 aa)
	LOC102357450	Uncharacterized protein; Belongs to the heat shock protein 70 family. (641 aa)
	MITF	Melanocyte inducing transcription factor. (486 aa)
	SLC24A5	Solute carrier family 24 member 5; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (572 aa)
	CASP3	Caspase 3; Belongs to the peptidase C14A family. (290 aa)
	PAX3	Paired box 3. (488 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CASP3	LOC102357450	ENSLACP00000007386	ENSLACP00000014115	Caspase 3; Belongs to the peptidase C14A family.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.423
LOC102357450	CASP3	ENSLACP00000014115	ENSLACP00000007386	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Caspase 3; Belongs to the peptidase C14A family.	0.423
MITF	PAX3	ENSLACP00000013112	ENSLACP00000007147	Melanocyte inducing transcription factor.	Paired box 3.	0.596
MITF	SLC24A5	ENSLACP00000013112	ENSLACP00000006751	Melanocyte inducing transcription factor.	Solute carrier family 24 member 5; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.	0.654
MITF	SLC25A5	ENSLACP00000013112	ENSLACP00000012098	Melanocyte inducing transcription factor.	Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.502
MITF	TYR	ENSLACP00000013112	ENSLACP00000011256	Melanocyte inducing transcription factor.	Tyrosinase.	0.743
PAX3	MITF	ENSLACP00000007147	ENSLACP00000013112	Paired box 3.	Melanocyte inducing transcription factor.	0.596
PAX3	SLC25A5	ENSLACP00000007147	ENSLACP00000012098	Paired box 3.	Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.413
PAX3	TYR	ENSLACP00000007147	ENSLACP00000011256	Paired box 3.	Tyrosinase.	0.585
SLC24A5	MITF	ENSLACP00000006751	ENSLACP00000013112	Solute carrier family 24 member 5; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.	Melanocyte inducing transcription factor.	0.654
SLC24A5	SLC25A5	ENSLACP00000006751	ENSLACP00000012098	Solute carrier family 24 member 5; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.	Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.538
SLC24A5	TYR	ENSLACP00000006751	ENSLACP00000011256	Solute carrier family 24 member 5; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.	Tyrosinase.	0.805
SLC25A5	MITF	ENSLACP00000012098	ENSLACP00000013112	Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family.	Melanocyte inducing transcription factor.	0.502
SLC25A5	PAX3	ENSLACP00000012098	ENSLACP00000007147	Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family.	Paired box 3.	0.413
SLC25A5	SLC24A5	ENSLACP00000012098	ENSLACP00000006751	Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family.	Solute carrier family 24 member 5; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.	0.538
TYR	MITF	ENSLACP00000011256	ENSLACP00000013112	Tyrosinase.	Melanocyte inducing transcription factor.	0.743
TYR	PAX3	ENSLACP00000011256	ENSLACP00000007147	Tyrosinase.	Paired box 3.	0.585
TYR	SLC24A5	ENSLACP00000011256	ENSLACP00000006751	Tyrosinase.	Solute carrier family 24 member 5; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.	0.805