STRINGSTRING
RUNX2 RUNX2 MMP9 MMP9 MMP13 MMP13 ACTB ACTB AXIN2 AXIN2 FZD2 FZD2 ULK1 ULK1 MAP1LC3A MAP1LC3A SOX5 SOX5 ADIPOQ ADIPOQ CEBPB CEBPB LOC102348027 LOC102348027 ATG7 ATG7 IHH IHH PCNA PCNA CASP3 CASP3 WNT16 WNT16 IL6 IL6 CXCL12 CXCL12 GAPDH GAPDH
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RUNX2Runt-related transcription factor. (452 aa)
MMP9Matrix metallopeptidase 9. (682 aa)
MMP13Matrix metallopeptidase 13. (467 aa)
ACTBUncharacterized protein. (376 aa)
AXIN2Axin 2. (841 aa)
FZD2Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (552 aa)
ULK1Unc-51 like autophagy activating kinase 1. (1046 aa)
MAP1LC3AMicrotubule associated protein 1 light chain 3 alpha. (121 aa)
SOX5SRY-box transcription factor 5. (757 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (259 aa)
CEBPBCCAAT/enhancer-binding protein. (291 aa)
LOC102348027Casein kinase 2, alpha 4 polypeptide; Belongs to the protein kinase superfamily. (401 aa)
ATG7Autophagy related 7. (593 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (410 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (290 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
IL6Uncharacterized protein. (149 aa)
CXCL12C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (95 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (359 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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