(19 nodes) (2014) Clocks for all seasons: unwinding the roles and mechanisms of circadian and interval timers in the hypothalamus and pituitary. network (Latimeria chalumnae)

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Your Input:
	CRY2	Cryptochrome circadian regulator 2. (434 aa)
	SIX1	SIX homeobox 1. (283 aa)
	PER2	PAS domain-containing protein. (1371 aa)
	NAMPT	Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family. (492 aa)
	EYA3	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (593 aa)
	EGR1	Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (505 aa)
	NPAS4	Neuronal PAS domain protein 4. (731 aa)
	CSNK1E	Casein kinase 1, epsilon; Belongs to the protein kinase superfamily. (418 aa)
	CRY1	Cryptochrome circadian regulator 1. (653 aa)
	ARNT2	Uncharacterized protein. (206 aa)
	H3ALZ2_LATCH	Uncharacterized protein. (108 aa)
	TRH	Pro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems. (262 aa)
	ARNT2-2	Aryl-hydrocarbon receptor nuclear translocator 2. (430 aa)
	LOC102365364	Cryptochrome circadian regulator 3a. (616 aa)
	PRL	Prolactin. (231 aa)
	GFAP	Glial fibrillary acidic protein; Belongs to the intermediate filament family. (449 aa)
	CLOCK	Clock circadian regulator. (846 aa)
	ARNT	Aryl hydrocarbon receptor nuclear translocator. (801 aa)
	AANAT	Aralkylamine N-acetyltransferase. (205 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AANAT	CSNK1E	ENSLACP00000017693	ENSLACP00000009077	Aralkylamine N-acetyltransferase.	Casein kinase 1, epsilon; Belongs to the protein kinase superfamily.	0.408
AANAT	EYA3	ENSLACP00000017693	ENSLACP00000005466	Aralkylamine N-acetyltransferase.	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	0.468
ARNT	CRY1	ENSLACP00000015797	ENSLACP00000009266	Aryl hydrocarbon receptor nuclear translocator.	Cryptochrome circadian regulator 1.	0.554
ARNT	CRY2	ENSLACP00000015797	ENSLACP00000021043	Aryl hydrocarbon receptor nuclear translocator.	Cryptochrome circadian regulator 2.	0.449
ARNT	LOC102365364	ENSLACP00000015797	ENSLACP00000011974	Aryl hydrocarbon receptor nuclear translocator.	Cryptochrome circadian regulator 3a.	0.498
ARNT	NAMPT	ENSLACP00000015797	ENSLACP00000005041	Aryl hydrocarbon receptor nuclear translocator.	Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family.	0.644
ARNT	NPAS4	ENSLACP00000015797	ENSLACP00000007488	Aryl hydrocarbon receptor nuclear translocator.	Neuronal PAS domain protein 4.	0.948
ARNT	PER2	ENSLACP00000015797	ENSLACP00000022930	Aryl hydrocarbon receptor nuclear translocator.	PAS domain-containing protein.	0.461
ARNT2	ARNT2-2	ENSLACP00000010079	ENSLACP00000011352	Uncharacterized protein.	Aryl-hydrocarbon receptor nuclear translocator 2.	0.900
ARNT2	CLOCK	ENSLACP00000010079	ENSLACP00000015264	Uncharacterized protein.	Clock circadian regulator.	0.513
ARNT2	CRY1	ENSLACP00000010079	ENSLACP00000009266	Uncharacterized protein.	Cryptochrome circadian regulator 1.	0.485
ARNT2	NAMPT	ENSLACP00000010079	ENSLACP00000005041	Uncharacterized protein.	Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family.	0.620
ARNT2	NPAS4	ENSLACP00000010079	ENSLACP00000007488	Uncharacterized protein.	Neuronal PAS domain protein 4.	0.948
ARNT2	PER2	ENSLACP00000010079	ENSLACP00000022930	Uncharacterized protein.	PAS domain-containing protein.	0.461
ARNT2	TRH	ENSLACP00000010079	ENSLACP00000011077	Uncharacterized protein.	Pro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems.	0.431
ARNT2-2	ARNT2	ENSLACP00000011352	ENSLACP00000010079	Aryl-hydrocarbon receptor nuclear translocator 2.	Uncharacterized protein.	0.900
ARNT2-2	CLOCK	ENSLACP00000011352	ENSLACP00000015264	Aryl-hydrocarbon receptor nuclear translocator 2.	Clock circadian regulator.	0.533
ARNT2-2	CRY1	ENSLACP00000011352	ENSLACP00000009266	Aryl-hydrocarbon receptor nuclear translocator 2.	Cryptochrome circadian regulator 1.	0.485
ARNT2-2	NAMPT	ENSLACP00000011352	ENSLACP00000005041	Aryl-hydrocarbon receptor nuclear translocator 2.	Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family.	0.620
ARNT2-2	NPAS4	ENSLACP00000011352	ENSLACP00000007488	Aryl-hydrocarbon receptor nuclear translocator 2.	Neuronal PAS domain protein 4.	0.948