(15 nodes) (2015) Origins of adult pigmentation: diversity in pigment stem cell lineages and implications for pattern evolution. network (Latimeria chalumnae)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

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Your Input:
	BNC2-2	Uncharacterized protein. (124 aa)
	SOX5	SRY-box transcription factor 5. (757 aa)
	PAX7	Paired box 7. (420 aa)
	LOC102357848	Solute carrier family 2 member 11b; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (494 aa)
	TSHR	Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (689 aa)
	CSF1R	Colony stimulating factor 1 receptor. (968 aa)
	FOXD3	Forkhead box D3. (373 aa)
	TYR	Tyrosinase. (532 aa)
	MTREX	Mtr4 exosome RNA helicase. (1031 aa)
	SORBS3	Sorbin and SH3 domain containing 3. (298 aa)
	TBX6	Uncharacterized protein. (101 aa)
	SOX10	SRY-box transcription factor 10. (451 aa)
	BNC2	Basonuclin 2. (880 aa)
	ERBB3	Protein kinase domain-containing protein. (1047 aa)
	NRG1	Neuregulin 1. (409 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BNC2	BNC2-2	ENSLACP00000003888	ENSLACP00000023198	Basonuclin 2.	Uncharacterized protein.	0.900
BNC2-2	BNC2	ENSLACP00000023198	ENSLACP00000003888	Uncharacterized protein.	Basonuclin 2.	0.900
CSF1R	LOC102357848	ENSLACP00000016266	ENSLACP00000019964	Colony stimulating factor 1 receptor.	Solute carrier family 2 member 11b; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.	0.437
CSF1R	TYR	ENSLACP00000016266	ENSLACP00000011256	Colony stimulating factor 1 receptor.	Tyrosinase.	0.631
ERBB3	NRG1	ENSLACP00000001477	ENSLACP00000001129	Protein kinase domain-containing protein.	Neuregulin 1.	0.903
ERBB3	SORBS3	ENSLACP00000001477	ENSLACP00000009200	Protein kinase domain-containing protein.	Sorbin and SH3 domain containing 3.	0.510
FOXD3	SOX10	ENSLACP00000017581	ENSLACP00000004990	Forkhead box D3.	SRY-box transcription factor 10.	0.695
FOXD3	TYR	ENSLACP00000017581	ENSLACP00000011256	Forkhead box D3.	Tyrosinase.	0.532
LOC102357848	CSF1R	ENSLACP00000019964	ENSLACP00000016266	Solute carrier family 2 member 11b; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.	Colony stimulating factor 1 receptor.	0.437
LOC102357848	TYR	ENSLACP00000019964	ENSLACP00000011256	Solute carrier family 2 member 11b; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.	Tyrosinase.	0.414
MTREX	SORBS3	ENSLACP00000010303	ENSLACP00000009200	Mtr4 exosome RNA helicase.	Sorbin and SH3 domain containing 3.	0.503
NRG1	ERBB3	ENSLACP00000001129	ENSLACP00000001477	Neuregulin 1.	Protein kinase domain-containing protein.	0.903
NRG1	SORBS3	ENSLACP00000001129	ENSLACP00000009200	Neuregulin 1.	Sorbin and SH3 domain containing 3.	0.536
PAX7	SOX10	ENSLACP00000021802	ENSLACP00000004990	Paired box 7.	SRY-box transcription factor 10.	0.570
SORBS3	ERBB3	ENSLACP00000009200	ENSLACP00000001477	Sorbin and SH3 domain containing 3.	Protein kinase domain-containing protein.	0.510
SORBS3	MTREX	ENSLACP00000009200	ENSLACP00000010303	Sorbin and SH3 domain containing 3.	Mtr4 exosome RNA helicase.	0.503
SORBS3	NRG1	ENSLACP00000009200	ENSLACP00000001129	Sorbin and SH3 domain containing 3.	Neuregulin 1.	0.536
SOX10	FOXD3	ENSLACP00000004990	ENSLACP00000017581	SRY-box transcription factor 10.	Forkhead box D3.	0.695
SOX10	PAX7	ENSLACP00000004990	ENSLACP00000021802	SRY-box transcription factor 10.	Paired box 7.	0.570
SOX10	SOX5	ENSLACP00000004990	ENSLACP00000022286	SRY-box transcription factor 10.	SRY-box transcription factor 5.	0.492