STRINGSTRING
CTCF CTCF ERBB4 ERBB4 CASP10 CASP10 NEUROG2 NEUROG2 ATG7 ATG7 H3A2B0_LATCH H3A2B0_LATCH ERBB4-2 ERBB4-2 TBR1 TBR1 IGF2 IGF2 WLS WLS FMR1 FMR1 GBX2 GBX2 LOC102356182 LOC102356182 GDF7 GDF7 PCNA PCNA BARHL1 BARHL1 NTF3 NTF3 FGF8 FGF8 RBPJ RBPJ ATF6 ATF6 FGF11 FGF11 CDK5 CDK5 SIL1 SIL1 FGF16 FGF16 ATRX ATRX FGF22 FGF22 EFNB2 EFNB2 CXCR4 CXCR4 MECP2 MECP2 BDNF BDNF SHH SHH FGF13 FGF13 FGF3 FGF3 FGF4 FGF4 APAF1 APAF1 PCCA PCCA FGF19 FGF19 FGF20 FGF20 PLAT PLAT ATG5 ATG5 FGF1 FGF1 FGF18 FGF18 PTF1A PTF1A FGF7 FGF7 FGF5 FGF5 LMX1A LMX1A PAX6 PAX6 FGF14 FGF14 ADCYAP1 ADCYAP1 FGF2 FGF2 HOXA2 HOXA2 FGF12 FGF12 EN1 EN1 GLI2 GLI2 PAX2 PAX2 CUX1 CUX1 FGF6 FGF6 CASP9 CASP9 ULK1 ULK1 ACP2 ACP2 OTX2 OTX2 WNT1 WNT1 NOTCH2 NOTCH2 RELN RELN VLDLR VLDLR PROM1 PROM1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CTCFCCCTC-binding factor. (773 aa)
ERBB4Protein kinase domain-containing protein. (479 aa)
CASP10Caspase 10; Belongs to the peptidase C14A family. (539 aa)
NEUROG2Neurogenin 2. (204 aa)
ATG7Autophagy related 7. (593 aa)
H3A2B0_LATCHFibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
ERBB4-2Protein kinase domain-containing protein. (789 aa)
TBR1T-box brain transcription factor 1. (673 aa)
IGF2Insulin like growth factor 2. (207 aa)
WLSWnt ligand secretion mediator. (541 aa)
FMR1Fragile X mental retardation 1. (627 aa)
GBX2Gastrulation brain homeobox 2. (344 aa)
LOC102356182Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (196 aa)
GDF7Growth differentiation factor 7. (416 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
BARHL1BarH like homeobox 1. (323 aa)
NTF3Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (255 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
RBPJRecombination signal binding protein for immunoglobulin kappa J region. (487 aa)
ATF6Activating transcription factor 6. (355 aa)
FGF11Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (246 aa)
CDK5Cyclin dependent kinase 5. (290 aa)
SIL1SIL1 nucleotide exchange factor. (468 aa)
FGF16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
ATRXATRX chromatin remodeler. (2488 aa)
FGF22Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (99 aa)
EFNB2Ephrin B2; Belongs to the ephrin family. (338 aa)
CXCR4C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (363 aa)
MECP2Methyl-CpG binding protein 2. (459 aa)
BDNFBrain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family. (254 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (421 aa)
FGF13Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (255 aa)
FGF3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (237 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (195 aa)
APAF1Apoptotic peptidase activating factor 1. (1202 aa)
PCCAPropionyl-CoA carboxylase subunit alpha. (711 aa)
FGF19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (217 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
PLATPlasminogen activator; Belongs to the peptidase S1 family. (552 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
PTF1APancreas associated transcription factor 1a. (266 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
FGF5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
LMX1ALIM homeobox transcription factor 1 alpha. (294 aa)
PAX6Paired box 6. (463 aa)
FGF14Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (163 aa)
ADCYAP1Adenylate cyclase activating polypeptide 1. (199 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
HOXA2Homeobox A2b. (366 aa)
FGF12Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (243 aa)
EN1Homeobox protein engrailed-like. (271 aa)
GLI2GLI family zinc finger 2. (1366 aa)
PAX2Paired box 2. (456 aa)
CUX1Homeobox protein cut-like. (1477 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
CASP9Caspase 9; Belongs to the peptidase C14A family. (457 aa)
ULK1Unc-51 like autophagy activating kinase 1. (1046 aa)
ACP2Acid phosphatase 2, lysosomal; Belongs to the histidine acid phosphatase family. (438 aa)
OTX2Orthodenticle homeobox 2. (308 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (373 aa)
NOTCH2Notch receptor 2. (2489 aa)
RELNReelin. (3462 aa)
VLDLRVery low density lipoprotein receptor. (885 aa)
PROM1Prominin 1. (603 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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