STRINGSTRING
FGF5 FGF5 HRAS HRAS FGF6 FGF6 FGF12 FGF12 ACTB ACTB FGF2 FGF2 H3A2B0_LATCH H3A2B0_LATCH LOC102356182 LOC102356182 FGF8 FGF8 FGF11 FGF11 FGF16 FGF16 FGF22 FGF22 SHH SHH FGF13 FGF13 FGF3 FGF3 FGF4 FGF4 FGF19 FGF19 FGF20 FGF20 FGF1 FGF1 FGF18 FGF18 FGF7 FGF7 FGF14 FGF14
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FGF5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
HRASHRas proto-oncogene, GTPase. (193 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
FGF12Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (243 aa)
ACTBUncharacterized protein. (376 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
H3A2B0_LATCHFibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
LOC102356182Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (196 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
FGF11Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (246 aa)
FGF16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
FGF22Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (99 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (421 aa)
FGF13Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (255 aa)
FGF3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (237 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (195 aa)
FGF19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (217 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
FGF14Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (163 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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