Genes that are sometimes fused into single open reading frames.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
Node Content
empty nodes: proteins of unknown 3D structure
filled nodes: a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (410 aa)
IRF6
Interferon regulatory factor 6. (446 aa)
IRX1
Iroquois homeobox 1. (460 aa)
PTCH1
Patched 1. (1287 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897 Other names: L. chalumnae, coelacanth