STRINGSTRING
RPL39 RPL39 TSC2 TSC2 ITGB1 ITGB1 FLNA FLNA RPSA RPSA SERPINA1 SERPINA1 CFB CFB SEC24C SEC24C RPL7 RPL7 RRS1 RRS1 LOC102359475 LOC102359475 FBXO32 FBXO32 JUN JUN ATP5J ATP5J PABPC1L PABPC1L PKM PKM RPL4 RPL4 PPP1R3C PPP1R3C LOC102347576 LOC102347576 FLNC FLNC EIF4E EIF4E AGL AGL MRPL39 MRPL39 ALDOA ALDOA CKMT2 CKMT2 NDRG2 NDRG2 RPL11 RPL11 LDHA LDHA RYR3 RYR3 RPL5 RPL5 CKB CKB GAPDH GAPDH RPL37A RPL37A POMC POMC PABPC4 PABPC4 FOXL2 FOXL2 PPM1B PPM1B CKMT1A CKMT1A PGK1 PGK1 LOC102346309 LOC102346309 FLNB FLNB RPL19 RPL19 CKM CKM SIX3 SIX3 CACNB1 CACNB1 RPL36 RPL36 RPL12 RPL12 RPS16 RPS16 JUND JUND MYBPC2 MYBPC2 ENO1 ENO1 H3B8U3_LATCH H3B8U3_LATCH MTOR MTOR FABP3 FABP3 ACTN3 ACTN3 GYS1 GYS1 CCND2 CCND2 CAPN1 CAPN1 PYGM PYGM RYR1 RYR1 SIX1 SIX1 G0S2 G0S2 PFKM PFKM ND1 ND1 GADL1 GADL1 PKLR PKLR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RPL39Ribosomal protein L39. (51 aa)
TSC2TSC complex subunit 2. (1836 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (822 aa)
FLNAFilamin A. (2637 aa)
RPSA40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Belongs to the universal ribosomal protein uS2 family. (313 aa)
SERPINA1SERPIN domain-containing protein; Belongs to the serpin family. (418 aa)
CFBUncharacterized protein; Belongs to the peptidase S1 family. (764 aa)
SEC24CSEC24 homolog C, COPII coat complex component. (1120 aa)
RPL7Ribosomal protein L7. (230 aa)
RRS1Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (329 aa)
LOC102359475Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (668 aa)
FBXO32F-box protein 32. (353 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (311 aa)
ATP5JATP synthase-coupling factor 6, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain; Belongs to the eukaryotic ATPase subunit F6 family. (110 aa)
PABPC1LPolyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (639 aa)
PKMPyruvate kinase; Belongs to the pyruvate kinase family. (539 aa)
RPL4Ribosomal protein L4. (360 aa)
PPP1R3CProtein phosphatase 1 regulatory subunit 3C; Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown. (319 aa)
LOC102347576SH3 domain-containing protein. (2968 aa)
FLNCFilamin C. (2664 aa)
EIF4EEukaryotic translation initiation factor 4E; Belongs to the eukaryotic initiation factor 4E family. (217 aa)
AGLAmylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase. (1533 aa)
MRPL39Mitochondrial ribosomal protein L39. (295 aa)
ALDOAFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
CKMT2Creatine kinase, mitochondrial 2; Belongs to the ATP:guanido phosphotransferase family. (419 aa)
NDRG2NDRG family member 2. (355 aa)
RPL11Ribosomal protein L11; Belongs to the universal ribosomal protein uL5 family. (184 aa)
LDHAL-lactate dehydrogenase. (362 aa)
RYR3Uncharacterized protein. (3558 aa)
RPL5Ribosomal protein L5. (296 aa)
CKBCreatine kinase B; Belongs to the ATP:guanido phosphotransferase family. (389 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (359 aa)
RPL37ARibosomal protein L37a. (92 aa)
POMCProopiomelanocortin. (255 aa)
PABPC4Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (638 aa)
FOXL2Forkhead box L2. (305 aa)
PPM1BPPM-type phosphatase domain-containing protein. (474 aa)
CKMT1ACreatine kinase, mitochondrial 1; Belongs to the ATP:guanido phosphotransferase family. (418 aa)
PGK1Phosphoglycerate kinase. (389 aa)
LOC102346309Nebulin. (3294 aa)
FLNBFilamin B. (2605 aa)
RPL19Ribosomal protein L19; Belongs to the eukaryotic ribosomal protein eL19 family. (196 aa)
CKMCreatine kinase, M-type; Belongs to the ATP:guanido phosphotransferase family. (381 aa)
SIX3SIX homeobox 3. (291 aa)
CACNB1Calcium voltage-gated channel auxiliary subunit beta 1. (625 aa)
RPL3660S ribosomal protein L36; Belongs to the eukaryotic ribosomal protein eL36 family. (119 aa)
RPL12Ribosomal protein L12; Belongs to the universal ribosomal protein uL11 family. (185 aa)
RPS16Ribosomal protein S16; Belongs to the universal ribosomal protein uS9 family. (202 aa)
JUNDBZIP domain-containing protein. (293 aa)
MYBPC2Myosin binding protein C, fast type. (1107 aa)
ENO1Enolase 1. (438 aa)
H3B8U3_LATCHSerine/threonine-protein kinase TOR. (1418 aa)
MTORMechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family. (1009 aa)
FABP3Fatty acid binding protein 3; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (133 aa)
ACTN3Actinin alpha 3a. (907 aa)
GYS1Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (721 aa)
CCND2Cyclin D2, b; Belongs to the cyclin family. (291 aa)
CAPN1Calpain 1; Belongs to the peptidase C2 family. (642 aa)
PYGMAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (1365 aa)
RYR1Ryanodine receptor 1. (5024 aa)
SIX1SIX homeobox 1. (283 aa)
G0S2G0/G1 switch 2. (100 aa)
PFKMPhosphofructokinase, muscle. (830 aa)
ND1NADH-ubiquinone oxidoreductase chain 1; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (323 aa)
GADL1Glutamate decarboxylase like 1. (519 aa)
PKLRPyruvate kinase; Belongs to the pyruvate kinase family. (530 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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