STRINGSTRING
H2ZZF1_LATCH H2ZZF1_LATCH CASP7 CASP7 PXDNL PXDNL HDAC7 HDAC7 H3BH94_LATCH H3BH94_LATCH CASP9 CASP9 HDAC5 HDAC5 LOC102367521 LOC102367521 PXDN PXDN MCL1 MCL1 HDAC3 HDAC3 HDAC4 HDAC4 PCNA PCNA H4C11 H4C11 AHR AHR PARP1 PARP1 CCNE1 CCNE1 CASP10 CASP10
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
H2ZZF1_LATCHPAS domain-containing protein. (1038 aa)
CASP7Caspase 7; Belongs to the peptidase C14A family. (313 aa)
PXDNLPeroxidasin like. (1276 aa)
HDAC7Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (873 aa)
H3BH94_LATCHPAS domain-containing protein. (733 aa)
CASP9Caspase 9; Belongs to the peptidase C14A family. (457 aa)
HDAC5Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1084 aa)
LOC102367521Uncharacterized protein; Belongs to the peptidase C14A family. (253 aa)
PXDNPeroxidasin. (1149 aa)
MCL1MCL1 apoptosis regulator, BCL2 family member. (207 aa)
HDAC3Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (428 aa)
HDAC4Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1086 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
H4C11Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
AHRAryl hydrocarbon receptor 1a. (868 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1011 aa)
CCNE1Cyclin E1; Belongs to the cyclin family. (417 aa)
CASP10Caspase 10; Belongs to the peptidase C14A family. (539 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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