(16 nodes) (2016) Eppur Si Muove: Evidence for an External Granular Layer and Possibly Transit Amplification in the Teleostean Cerebellum. network (Latimeria chalumnae)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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Known Interactions

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Predicted Interactions

gene neighborhood

gene fusions

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Your Input:
	WNT1	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (373 aa)
	H3F3B	Histone H3; Belongs to the histone H3 family. (136 aa)
	SMO	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (820 aa)
	GLI3	GLI family zinc finger 3. (1456 aa)
	PVALB	Parvalbumin alpha; In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions (By similarity). (112 aa)
	LOC102347143	Uncharacterized protein. (612 aa)
	OLIG2	Oligodendrocyte transcription factor 2. (273 aa)
	PCNA	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
	H3ABV0_LATCH	Tyrosine hydroxylase. (247 aa)
	LOC102355712	Histone H3; Belongs to the histone H3 family. (129 aa)
	CA8	Carbonic anhydrase 8; Belongs to the alpha-carbonic anhydrase family. (279 aa)
	GAD1	Glutamate decarboxylase 1. (590 aa)
	PTF1A	Pancreas associated transcription factor 1a. (266 aa)
	H3F3B-2	Histone H3; Belongs to the histone H3 family. (136 aa)
	PAX6	Paired box 6. (463 aa)
	GLI2	GLI family zinc finger 2. (1366 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CA8	PVALB	ENSLACP00000012101	ENSLACP00000004606	Carbonic anhydrase 8; Belongs to the alpha-carbonic anhydrase family.	Parvalbumin alpha; In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions (By similarity).	0.499
GAD1	PVALB	ENSLACP00000014477	ENSLACP00000004606	Glutamate decarboxylase 1.	Parvalbumin alpha; In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions (By similarity).	0.704
GLI2	GLI3	ENSLACP00000019749	ENSLACP00000004224	GLI family zinc finger 2.	GLI family zinc finger 3.	0.703
GLI2	PAX6	ENSLACP00000019749	ENSLACP00000017411	GLI family zinc finger 2.	Paired box 6.	0.413
GLI2	SMO	ENSLACP00000019749	ENSLACP00000002758	GLI family zinc finger 2.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.914
GLI3	GLI2	ENSLACP00000004224	ENSLACP00000019749	GLI family zinc finger 3.	GLI family zinc finger 2.	0.703
GLI3	PAX6	ENSLACP00000004224	ENSLACP00000017411	GLI family zinc finger 3.	Paired box 6.	0.485
GLI3	SMO	ENSLACP00000004224	ENSLACP00000002758	GLI family zinc finger 3.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.894
H3ABV0_LATCH	PAX6	ENSLACP00000007121	ENSLACP00000017411	Tyrosine hydroxylase.	Paired box 6.	0.462
H3ABV0_LATCH	PVALB	ENSLACP00000007121	ENSLACP00000004606	Tyrosine hydroxylase.	Parvalbumin alpha; In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions (By similarity).	0.582
LOC102347143	PVALB	ENSLACP00000004517	ENSLACP00000004606	Uncharacterized protein.	Parvalbumin alpha; In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions (By similarity).	0.549
OLIG2	PAX6	ENSLACP00000006181	ENSLACP00000017411	Oligodendrocyte transcription factor 2.	Paired box 6.	0.669
OLIG2	SMO	ENSLACP00000006181	ENSLACP00000002758	Oligodendrocyte transcription factor 2.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.437
PAX6	GLI2	ENSLACP00000017411	ENSLACP00000019749	Paired box 6.	GLI family zinc finger 2.	0.413
PAX6	GLI3	ENSLACP00000017411	ENSLACP00000004224	Paired box 6.	GLI family zinc finger 3.	0.485
PAX6	H3ABV0_LATCH	ENSLACP00000017411	ENSLACP00000007121	Paired box 6.	Tyrosine hydroxylase.	0.462
PAX6	OLIG2	ENSLACP00000017411	ENSLACP00000006181	Paired box 6.	Oligodendrocyte transcription factor 2.	0.669
PAX6	PTF1A	ENSLACP00000017411	ENSLACP00000015592	Paired box 6.	Pancreas associated transcription factor 1a.	0.495
PAX6	SMO	ENSLACP00000017411	ENSLACP00000002758	Paired box 6.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.469
PAX6	WNT1	ENSLACP00000017411	ENSLACP00000021628	Paired box 6.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.513