(5 nodes) (2016) Enamel ribbons, surface nodules, and octacalcium phosphate in C57BL6 Amelx-- mice and Amelx+- lyonization. network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ARHGAP6	Rho GTPase activating protein 6. (720 aa)
	LOC102359827	Uncharacterized protein. (536 aa)
	LAMP1	Lysosomal associated membrane protein 1. (412 aa)
	PORCN	Porcupine O-acyltransferase; Belongs to the membrane-bound acyltransferase family. (463 aa)
	CD63	Tetraspanin. (270 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARHGAP6	LOC102359827	ENSLACP00000016241	ENSLACP00000003277	Rho GTPase activating protein 6.	Uncharacterized protein.	0.496
ARHGAP6	PORCN	ENSLACP00000016241	ENSLACP00000008461	Rho GTPase activating protein 6.	Porcupine O-acyltransferase; Belongs to the membrane-bound acyltransferase family.	0.589
CD63	LAMP1	ENSLACP00000018046	ENSLACP00000006760	Tetraspanin.	Lysosomal associated membrane protein 1.	0.862
CD63	LOC102359827	ENSLACP00000018046	ENSLACP00000003277	Tetraspanin.	Uncharacterized protein.	0.550
LAMP1	CD63	ENSLACP00000006760	ENSLACP00000018046	Lysosomal associated membrane protein 1.	Tetraspanin.	0.862
LOC102359827	ARHGAP6	ENSLACP00000003277	ENSLACP00000016241	Uncharacterized protein.	Rho GTPase activating protein 6.	0.496
LOC102359827	CD63	ENSLACP00000003277	ENSLACP00000018046	Uncharacterized protein.	Tetraspanin.	0.550
PORCN	ARHGAP6	ENSLACP00000008461	ENSLACP00000016241	Porcupine O-acyltransferase; Belongs to the membrane-bound acyltransferase family.	Rho GTPase activating protein 6.	0.589