STRINGSTRING
RBPJ RBPJ HDAC4 HDAC4 DGAT2 DGAT2 A1CF A1CF SLC10A2 SLC10A2 ELF5 ELF5 RBP2 RBP2 EHF EHF HES1 HES1 NR1D1 NR1D1 HDAC3 HDAC3 ACSL5 ACSL5 FABP6 FABP6 STAT3 STAT3 GFI1B GFI1B FABP2 FABP2 EHHADH EHHADH LOC102351684 LOC102351684 GATA5 GATA5 ADA ADA PYY PYY ETS1 ETS1 HDAC5 HDAC5 LOC102363206 LOC102363206 CDX2 CDX2 ANGPTL4 ANGPTL4 SPDEF SPDEF SLC27A4 SLC27A4 YBX1 YBX1 AGPAT2 AGPAT2 GALNT6 GALNT6 LGMN LGMN HDAC7 HDAC7 ALDOB ALDOB NEUROD1 NEUROD1 LOC102365039 LOC102365039 IRF1 IRF1 EPAS1 EPAS1 ENPEP ENPEP CFTR CFTR GABPA GABPA HNF4G HNF4G IKBKG IKBKG KLF5 KLF5 SCPEP1 SCPEP1 JUN JUN CEBPG CEBPG EGR1 EGR1 OSR2 OSR2 ATOH1 ATOH1 LAMP2 LAMP2 SMAD7 SMAD7 GATA4 GATA4 NFKBIZ NFKBIZ ELK4 ELK4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RBPJRecombination signal binding protein for immunoglobulin kappa J region. (487 aa)
HDAC4Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1086 aa)
DGAT2Diacylglycerol O-acyltransferase 2. (250 aa)
A1CFAPOBEC1 complementation factor. (583 aa)
SLC10A2Solute carrier family 10 member 2. (345 aa)
ELF5Uncharacterized protein. (259 aa)
RBP2Retinol binding protein 2; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (135 aa)
EHFETS homologous factor. (302 aa)
HES1Hes family bHLH transcription factor 1. (269 aa)
NR1D1Nuclear receptor subfamily 1 group D member 1. (614 aa)
HDAC3Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (428 aa)
ACSL5Acyl-CoA synthetase long chain family member 5. (683 aa)
FABP6Fatty acid binding protein 6. (127 aa)
STAT3Signal transducer and activator of transcription. (763 aa)
GFI1BGrowth factor independent 1B transcriptional repressor. (327 aa)
FABP2Fatty acid binding protein 2; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa)
EHHADHEnoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase. (537 aa)
LOC102351684Uncharacterized protein; Belongs to the peptidase C1 family. (346 aa)
GATA5GATA binding protein 5. (395 aa)
ADAA_deaminase domain-containing protein. (132 aa)
PYYPeptide YY. (97 aa)
ETS1ETS proto-oncogene 1, transcription factor. (443 aa)
HDAC5Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1084 aa)
LOC102363206Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (575 aa)
CDX2Caudal type homeobox 2. (258 aa)
ANGPTL4Angiopoietin like 4. (459 aa)
SPDEFSAM pointed domain containing ETS transcription factor. (341 aa)
SLC27A4Solute carrier family 27 member 4. (654 aa)
YBX1Y-box binding protein 1. (305 aa)
AGPAT21-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (211 aa)
GALNT6Polypeptide N-acetylgalactosaminyltransferase. (633 aa)
LGMNLegumain. (436 aa)
HDAC7Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (873 aa)
ALDOBFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
NEUROD1Neurogenic differentiation factor. (340 aa)
LOC102365039Cathepsin S; Belongs to the peptidase C1 family. (330 aa)
IRF1Interferon regulatory factor. (264 aa)
EPAS1Endothelial PAS domain protein 1. (861 aa)
ENPEPAminopeptidase. (952 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1491 aa)
GABPAGA binding protein transcription factor subunit alpha. (471 aa)
HNF4GHepatocyte nuclear factor 4 gamma. (332 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (435 aa)
KLF5Kruppel like factor 5. (435 aa)
SCPEP1Carboxypeptidase; Belongs to the peptidase S10 family. (437 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (311 aa)
CEBPGCCAAT enhancer binding protein gamma. (150 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (505 aa)
OSR2Odd-skipped related transciption factor 2. (314 aa)
ATOH1Atonal bHLH transcription factor 1. (279 aa)
LAMP2Lysosomal associated membrane protein 2. (416 aa)
SMAD7Mothers against decapentaplegic homolog. (377 aa)
GATA4GATA binding protein 4. (402 aa)
NFKBIZNFKB inhibitor zeta. (622 aa)
ELK4ETS transcription factor ELK4. (430 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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