(10 nodes) (2017) Aeromonas hydrophila utilizes TLR4 topology for synchronous activation of MyD88 and TRIF to orchestrate anti-inflammatory responses in zebrafish. network (Latimeria chalumnae)

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Your Input:
	TRAF6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (559 aa)
	TIRAP	TIR domain containing adaptor protein. (267 aa)
	MYD88	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (286 aa)
	IRAK4	Interleukin 1 receptor associated kinase 4. (454 aa)
	NOD1	Nucleotide binding oligomerization domain containing 1. (830 aa)
	TLR9	Toll-like receptor 9. (1039 aa)
	NOD2	Nucleotide binding oligomerization domain containing 2. (854 aa)
	TRAF3	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (567 aa)
	IL10	Interleukin 10. (185 aa)
	EEA1	Early endosome antigen 1. (1412 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EEA1	TLR9	ENSLACP00000001425	ENSLACP00000020965	Early endosome antigen 1.	Toll-like receptor 9.	0.680
IL10	IRAK4	ENSLACP00000005382	ENSLACP00000018448	Interleukin 10.	Interleukin 1 receptor associated kinase 4.	0.439
IL10	MYD88	ENSLACP00000005382	ENSLACP00000019094	Interleukin 10.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.796
IL10	NOD1	ENSLACP00000005382	ENSLACP00000016876	Interleukin 10.	Nucleotide binding oligomerization domain containing 1.	0.446
IL10	TLR9	ENSLACP00000005382	ENSLACP00000020965	Interleukin 10.	Toll-like receptor 9.	0.650
IL10	TRAF6	ENSLACP00000005382	ENSLACP00000003556	Interleukin 10.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.538
IRAK4	IL10	ENSLACP00000018448	ENSLACP00000005382	Interleukin 1 receptor associated kinase 4.	Interleukin 10.	0.439
IRAK4	MYD88	ENSLACP00000018448	ENSLACP00000019094	Interleukin 1 receptor associated kinase 4.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.998
IRAK4	TIRAP	ENSLACP00000018448	ENSLACP00000020333	Interleukin 1 receptor associated kinase 4.	TIR domain containing adaptor protein.	0.830
IRAK4	TLR9	ENSLACP00000018448	ENSLACP00000020965	Interleukin 1 receptor associated kinase 4.	Toll-like receptor 9.	0.720
IRAK4	TRAF3	ENSLACP00000018448	ENSLACP00000010314	Interleukin 1 receptor associated kinase 4.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.721
IRAK4	TRAF6	ENSLACP00000018448	ENSLACP00000003556	Interleukin 1 receptor associated kinase 4.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.986
MYD88	IL10	ENSLACP00000019094	ENSLACP00000005382	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	Interleukin 10.	0.796
MYD88	IRAK4	ENSLACP00000019094	ENSLACP00000018448	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	Interleukin 1 receptor associated kinase 4.	0.998
MYD88	NOD1	ENSLACP00000019094	ENSLACP00000016876	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	Nucleotide binding oligomerization domain containing 1.	0.643
MYD88	NOD2	ENSLACP00000019094	ENSLACP00000011767	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	Nucleotide binding oligomerization domain containing 2.	0.621
MYD88	TIRAP	ENSLACP00000019094	ENSLACP00000020333	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	TIR domain containing adaptor protein.	0.997
MYD88	TLR9	ENSLACP00000019094	ENSLACP00000020965	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	Toll-like receptor 9.	0.992
MYD88	TRAF3	ENSLACP00000019094	ENSLACP00000010314	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.802
MYD88	TRAF6	ENSLACP00000019094	ENSLACP00000003556	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.999