STRINGSTRING
BMP4 BMP4 TBX5 TBX5 PAX8 PAX8 IHH IHH SHH SHH IRX1 IRX1 PAX5 PAX5 TBX4 TBX4 WNT2 WNT2 PAX2 PAX2 WNT2B WNT2B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BMP4Bone morphogenetic protein 4. (460 aa)
TBX5T-box transcription factor 5. (522 aa)
PAX8Paired box 8. (458 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (410 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (421 aa)
IRX1Iroquois homeobox 1. (460 aa)
PAX5Paired box 5. (189 aa)
TBX4T-box transcription factor 4. (541 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa)
PAX2Paired box 2. (456 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.