(10 nodes) (2018) Vasculoprotective Effects of Pomegranate (Punica granatum L.). network (Latimeria chalumnae)

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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Your Input:
	NOS2	Nitric oxide synthase; Produces nitric oxide (NO). (1126 aa)
	LOC102347143	Uncharacterized protein. (612 aa)
	JUN	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (311 aa)
	IL6	Uncharacterized protein. (149 aa)
	PPARG	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (403 aa)
	LOC102358151	Angiotensin-converting enzyme. (1260 aa)
	ACE2	Angiotensin-converting enzyme. (814 aa)
	LOC102365332	Apolipoprotein Ea. (278 aa)
	VCAM1	Vascular cell adhesion molecule 1. (733 aa)
	EDN1	Endothelin 1. (216 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACE2	IL6	ENSLACP00000016231	ENSLACP00000009318	Angiotensin-converting enzyme.	Uncharacterized protein.	0.590
EDN1	IL6	ENSLACP00000018825	ENSLACP00000009318	Endothelin 1.	Uncharacterized protein.	0.531
EDN1	LOC102358151	ENSLACP00000018825	ENSLACP00000014522	Endothelin 1.	Angiotensin-converting enzyme.	0.463
EDN1	PPARG	ENSLACP00000018825	ENSLACP00000010456	Endothelin 1.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.508
EDN1	VCAM1	ENSLACP00000018825	ENSLACP00000017024	Endothelin 1.	Vascular cell adhesion molecule 1.	0.521
IL6	ACE2	ENSLACP00000009318	ENSLACP00000016231	Uncharacterized protein.	Angiotensin-converting enzyme.	0.590
IL6	EDN1	ENSLACP00000009318	ENSLACP00000018825	Uncharacterized protein.	Endothelin 1.	0.531
IL6	JUN	ENSLACP00000009318	ENSLACP00000005596	Uncharacterized protein.	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.	0.939
IL6	LOC102347143	ENSLACP00000009318	ENSLACP00000004517	Uncharacterized protein.	Uncharacterized protein.	0.649
IL6	LOC102358151	ENSLACP00000009318	ENSLACP00000014522	Uncharacterized protein.	Angiotensin-converting enzyme.	0.552
IL6	LOC102365332	ENSLACP00000009318	ENSLACP00000016337	Uncharacterized protein.	Apolipoprotein Ea.	0.515
IL6	PPARG	ENSLACP00000009318	ENSLACP00000010456	Uncharacterized protein.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.684
IL6	VCAM1	ENSLACP00000009318	ENSLACP00000017024	Uncharacterized protein.	Vascular cell adhesion molecule 1.	0.777
JUN	IL6	ENSLACP00000005596	ENSLACP00000009318	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.	Uncharacterized protein.	0.939
JUN	PPARG	ENSLACP00000005596	ENSLACP00000010456	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.468
LOC102347143	IL6	ENSLACP00000004517	ENSLACP00000009318	Uncharacterized protein.	Uncharacterized protein.	0.649
LOC102347143	LOC102358151	ENSLACP00000004517	ENSLACP00000014522	Uncharacterized protein.	Angiotensin-converting enzyme.	0.482
LOC102347143	LOC102365332	ENSLACP00000004517	ENSLACP00000016337	Uncharacterized protein.	Apolipoprotein Ea.	0.449
LOC102358151	EDN1	ENSLACP00000014522	ENSLACP00000018825	Angiotensin-converting enzyme.	Endothelin 1.	0.463
LOC102358151	IL6	ENSLACP00000014522	ENSLACP00000009318	Angiotensin-converting enzyme.	Uncharacterized protein.	0.552