(8 nodes) (2018) Variable gene transcription underlies phenotypic convergence of hypoxia tolerance in sculpins. network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ACADM	Acyl-CoA dehydrogenase medium chain. (424 aa)
	EIF4G2	Eukaryotic translation initiation factor 4 gamma 2. (933 aa)
	LOC102364955	4-hydroxyphenylpyruvate dioxygenase. (395 aa)
	HPDL	4-hydroxyphenylpyruvate dioxygenase. (442 aa)
	GAPDH	Glyceraldehyde-3-phosphate dehydrogenase. (359 aa)
	AGL	Amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase. (1533 aa)
	NDUFA1	NADH:ubiquinone oxidoreductase subunit A1. (108 aa)
	GAPDHS	Glyceraldehyde-3-phosphate dehydrogenase. (396 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACADM	HPDL	ENSLACP00000009742	ENSLACP00000015242	Acyl-CoA dehydrogenase medium chain.	4-hydroxyphenylpyruvate dioxygenase.	0.547
ACADM	LOC102364955	ENSLACP00000009742	ENSLACP00000017328	Acyl-CoA dehydrogenase medium chain.	4-hydroxyphenylpyruvate dioxygenase.	0.487
GAPDH	GAPDHS	ENSLACP00000012705	ENSLACP00000005423	Glyceraldehyde-3-phosphate dehydrogenase.	Glyceraldehyde-3-phosphate dehydrogenase.	0.901
GAPDHS	GAPDH	ENSLACP00000005423	ENSLACP00000012705	Glyceraldehyde-3-phosphate dehydrogenase.	Glyceraldehyde-3-phosphate dehydrogenase.	0.901
HPDL	ACADM	ENSLACP00000015242	ENSLACP00000009742	4-hydroxyphenylpyruvate dioxygenase.	Acyl-CoA dehydrogenase medium chain.	0.547
LOC102364955	ACADM	ENSLACP00000017328	ENSLACP00000009742	4-hydroxyphenylpyruvate dioxygenase.	Acyl-CoA dehydrogenase medium chain.	0.487