STRINGSTRING
PRDM4 PRDM4 KDM1A KDM1A SUV39H1 SUV39H1 SETD2 SETD2 KDM6B KDM6B JMJD4 JMJD4 KDM8 KDM8 KDM1B KDM1B SETD4 SETD4 SETD9 SETD9 EHMT2 EHMT2 PRDM14 PRDM14 PRDM2 PRDM2 PRDM6 PRDM6 PRDM8 PRDM8 SMYD1 SMYD1 KDM6A KDM6A SETD1B SETD1B KMT5B KMT5B PRDM10 PRDM10 KMT5A KMT5A NSD3 NSD3 PRDM1 PRDM1 PRDM16 PRDM16 PRDM16-2 PRDM16-2 KDM2B KDM2B PRDM11 PRDM11 KDM7A KDM7A KMT2A KMT2A KDM3B KDM3B PRDM12 PRDM12 PRDM15 PRDM15 ZNF488 ZNF488 SMYD3 SMYD3 KMT2E KMT2E KDM4A KDM4A KDM4B KDM4B SETD5 SETD5 JMJD6 JMJD6 H3B053_LATCH H3B053_LATCH SETD3 SETD3 EHMT1 EHMT1 SETD7 SETD7 EZH1 EZH1 LOC102354446 LOC102354446 KDM5A KDM5A SMYD2 SMYD2 KDM5B KDM5B KDM4C KDM4C JMJD1C JMJD1C SETDB1 SETDB1 NSD1 NSD1 JMJD8 JMJD8 NSD2 NSD2 SETDB2 SETDB2 DOT1L DOT1L SMYD5 SMYD5 PRDM5 PRDM5 KMT2C KMT2C PRDM13 PRDM13 SETMAR SETMAR SMYD4 SMYD4 JARID2 JARID2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PRDM4PR/SET domain 4. (795 aa)
KDM1ALysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (820 aa)
SUV39H1Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (291 aa)
SETD2SET domain containing 2, histone lysine methyltransferase. (2541 aa)
KDM6BLysine demethylase 6B. (1638 aa)
JMJD4Jumonji domain containing 4. (361 aa)
KDM8Lysine demethylase 8. (407 aa)
KDM1BLysine demethylase 1B. (768 aa)
SETD4SET domain containing 4. (416 aa)
SETD9SET domain containing 9. (298 aa)
EHMT2Euchromatic histone lysine methyltransferase 2. (936 aa)
PRDM14PR/SET domain 14. (599 aa)
PRDM2PR/SET domain 2. (1644 aa)
PRDM6PR/SET domain 6. (519 aa)
PRDM8PR/SET domain 8. (576 aa)
SMYD1SET and MYND domain containing 1. (479 aa)
KDM6ALysine (K)-specific demethylase 6A. (1452 aa)
SETD1BSET domain containing 1B, histone lysine methyltransferase. (1979 aa)
KMT5BLysine methyltransferase 5B. (948 aa)
PRDM10PR/SET domain 10. (1184 aa)
KMT5ALysine methyltransferase 5Ab. (348 aa)
NSD3Nuclear receptor binding SET domain protein 3. (1218 aa)
PRDM1SET domain-containing protein. (176 aa)
PRDM16PR/SET domain 16. (1135 aa)
PRDM16-2Si:ch211-263k4.2. (114 aa)
KDM2BUncharacterized protein. (1261 aa)
PRDM11SET domain-containing protein. (446 aa)
KDM7ALysine demethylase 7A. (907 aa)
KMT2AHistone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily. (3815 aa)
KDM3BLysine demethylase 3B. (1770 aa)
PRDM12PR domain zinc finger protein 12; Involved in the positive regulation of histone H3-K9 dimethylation; Belongs to the class V-like SAM-binding methyltransferase superfamily. (354 aa)
PRDM15PR/SET domain 15. (1169 aa)
ZNF488PR domain containing 8. (528 aa)
SMYD3SET and MYND domain containing 3. (239 aa)
KMT2ELysine methyltransferase 2E. (1846 aa)
KDM4AUncharacterized protein. (1075 aa)
KDM4BLysine demethylase 4B. (1136 aa)
SETD5Uncharacterized protein. (1122 aa)
JMJD6Jumonji domain containing 6, arginine demethylase and lysine hydroxylase. (403 aa)
H3B053_LATCHProtein-histidine N-methyltransferase. (302 aa)
SETD3Protein-histidine N-methyltransferase. (297 aa)
EHMT1Euchromatic histone lysine methyltransferase 1. (1352 aa)
SETD7SET domain containing 7, histone lysine methyltransferase. (351 aa)
EZH1Enhancer of zeste 1 polycomb repressive complex 2 subunit. (759 aa)
LOC102354446Lysine (K)-specific demethylase 5C. (1507 aa)
KDM5ALysine demethylase 5A. (1695 aa)
SMYD2SET and MYND domain containing 2. (437 aa)
KDM5BLysine demethylase 5B. (1659 aa)
KDM4CUncharacterized protein. (332 aa)
JMJD1CJumonji domain containing 1C. (2422 aa)
SETDB1SET domain bifurcated histone lysine methyltransferase 1. (1312 aa)
NSD1Nuclear receptor binding SET domain protein 1. (2226 aa)
JMJD8Jumonji domain containing 8. (268 aa)
NSD2Nuclear receptor binding SET domain protein 2. (1348 aa)
SETDB2SET domain bifurcated histone lysine methyltransferase 2. (751 aa)
DOT1LHistone-lysine N-methyltransferase, H3 lysine-79 specific. (988 aa)
SMYD5SMYD family member 5. (314 aa)
PRDM5Zinc finger protein. (578 aa)
KMT2CLysine methyltransferase 2C. (4872 aa)
PRDM13PR/SET domain 13. (630 aa)
SETMARSET domain and mariner transposase fusion gene. (198 aa)
SMYD4SET and MYND domain containing 4. (531 aa)
JARID2Jumonji and AT-rich interaction domain containing 2. (906 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.