STRINGSTRING
TYRP1 TYRP1 LOC102352006 LOC102352006 NRAS NRAS TRPM1 TRPM1 HIF1A HIF1A THBS1 THBS1 RUNX1-2 RUNX1-2 H3F3B-2 H3F3B-2 RAC1 RAC1 PRKACB PRKACB STAT3 STAT3 BRAF BRAF DCT DCT LOC102355712 LOC102355712 H3ADV1_LATCH H3ADV1_LATCH LOC102362951 LOC102362951 STAT1 STAT1 SRC SRC JAK2 JAK2 PTEN PTEN LOC102348367 LOC102348367 MMP21 MMP21 PLK1 PLK1 TGFBR2 TGFBR2 HEXIM1 HEXIM1 H3F3B H3F3B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TYRP1Tyrosinase related protein 1. (536 aa)
LOC102352006Uncharacterized protein. (163 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
TRPM1Transient receptor potential cation channel subfamily M member 1. (1235 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (813 aa)
THBS1Thrombospondin 1. (1170 aa)
RUNX1-2RUNX family transcription factor 1. (242 aa)
H3F3B-2Histone H3; Belongs to the histone H3 family. (136 aa)
RAC1Rac family small GTPase 1. (192 aa)
PRKACBUncharacterized protein; Belongs to the protein kinase superfamily. (351 aa)
STAT3Signal transducer and activator of transcription. (763 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (768 aa)
DCTDopachrome tautomerase. (521 aa)
LOC102355712Histone H3; Belongs to the histone H3 family. (129 aa)
H3ADV1_LATCHTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (974 aa)
LOC102362951Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily. (351 aa)
STAT1Signal transducer and activator of transcription. (1179 aa)
SRCTyrosine-protein kinase. (535 aa)
JAK2Tyrosine-protein kinase. (1152 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (404 aa)
LOC102348367ZnMc domain-containing protein; Belongs to the peptidase M10A family. (559 aa)
MMP21Matrix metallopeptidase 21; Belongs to the peptidase M10A family. (620 aa)
PLK1Serine/threonine-protein kinase PLK. (595 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (585 aa)
HEXIM1HEXIM P-TEFb complex subunit 1. (196 aa)
H3F3BHistone H3; Belongs to the histone H3 family. (136 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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