STRINGSTRING
ENPP1 ENPP1 COL1A2 COL1A2 BNC2 BNC2 CNNM2 CNNM2 BRCA1 BRCA1 SLC24A5 SLC24A5 IBSP IBSP MPPED2 MPPED2 SOST SOST PLOD2 PLOD2 RUNX2 RUNX2 MEF2C MEF2C IRF4 IRF4 BMP1 BMP1 TSHR TSHR CASP9 CASP9 LRP5 LRP5 BNC2-2 BNC2-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENPP1Ectonucleotide pyrophosphatase/phosphodiesterase 1. (850 aa)
COL1A2Collagen type I alpha 2 chain. (1367 aa)
BNC2Basonuclin 2. (880 aa)
CNNM2Cyclin and CBS domain divalent metal cation transport mediator 2. (789 aa)
BRCA1BRCA1 DNA repair associated. (1873 aa)
SLC24A5Solute carrier family 24 member 5; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (572 aa)
IBSPUncharacterized protein. (308 aa)
MPPED2Metallophosphoesterase domain containing 2. (294 aa)
SOSTSclerostin. (210 aa)
PLOD2Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2. (737 aa)
RUNX2Runt-related transcription factor. (452 aa)
MEF2CMyocyte enhancer factor 2C. (462 aa)
IRF4Interferon regulatory factor 4. (451 aa)
BMP1Metalloendopeptidase. (978 aa)
TSHRThyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (689 aa)
CASP9Caspase 9; Belongs to the peptidase C14A family. (457 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1598 aa)
BNC2-2Uncharacterized protein. (124 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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