STRINGSTRING
SRC SRC H3ACE0_LATCH H3ACE0_LATCH TFDP2 TFDP2 JAK2 JAK2 RPS3 RPS3 CCNB2 CCNB2 IRS2 IRS2 LOC102351883 LOC102351883 PLEK PLEK TFB2M TFB2M TGFB3 TGFB3 HK2 HK2 LOC102352268 LOC102352268 TGFB1 TGFB1 PFKM PFKM AKT3 AKT3 PKLR PKLR HIKESHI HIKESHI IRS1 IRS1 CCND1 CCND1 PLEK2 PLEK2 MDM2 MDM2 MND1 MND1 TRAF4 TRAF4 LOC102356355 LOC102356355 BCL2L10 BCL2L10 SH2B1 SH2B1 TGFB2 TGFB2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SRCTyrosine-protein kinase. (535 aa)
H3ACE0_LATCHInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (111 aa)
TFDP2Transcription factor. (450 aa)
JAK2Tyrosine-protein kinase. (1152 aa)
RPS3KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (254 aa)
CCNB2Cyclin B2; Belongs to the cyclin family. (404 aa)
IRS2Insulin receptor substrate 2. (1069 aa)
LOC102351883Ubiquitin specific peptidase 9; Belongs to the peptidase C19 family. (2505 aa)
PLEKPleckstrin. (353 aa)
TFB2MrRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (375 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (409 aa)
HK2Hexokinase 2. (918 aa)
LOC102352268Transforming growth factor beta; Belongs to the TGF-beta family. (414 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (401 aa)
PFKMPhosphofructokinase, muscle. (830 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (470 aa)
PKLRPyruvate kinase; Belongs to the pyruvate kinase family. (530 aa)
HIKESHIHeat shock protein nuclear import factor hikeshi. (229 aa)
IRS1Insulin receptor substrate 1. (1076 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (292 aa)
PLEK2Pleckstrin 2. (353 aa)
MDM2E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (485 aa)
MND1Meiotic nuclear division protein 1 homolog; Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis. Belongs to the MND1 family. (205 aa)
TRAF4TNF receptor-associated factor. (434 aa)
LOC102356355TNFR-Cys domain-containing protein. (163 aa)
BCL2L10BCL2 like 10. (178 aa)
SH2B1SH2B adaptor protein 1. (637 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (415 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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