STRINGSTRING
SMAD2 SMAD2 TGFB2 TGFB2 PRSS23 PRSS23 ACVR2B ACVR2B FURIN FURIN MSTN MSTN LOC102354780 LOC102354780 BMP1 BMP1 PRSS35 PRSS35 TGFB3 TGFB3 LOC102352268 LOC102352268 TGFB1 TGFB1 PAX7 PAX7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SMAD2Mothers against decapentaplegic homolog. (467 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (415 aa)
PRSS23Serine protease; Belongs to the peptidase S1B family. (382 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (515 aa)
FURINFurin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. (801 aa)
MSTNMyostatin. (372 aa)
LOC102354780Serine protease; Belongs to the peptidase S1B family. (370 aa)
BMP1Metalloendopeptidase. (978 aa)
PRSS35Serine protease; Belongs to the peptidase S1B family. (379 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (409 aa)
LOC102352268Transforming growth factor beta; Belongs to the TGF-beta family. (414 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (401 aa)
PAX7Paired box 7. (420 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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