STRINGSTRING
ATG12 ATG12 ATG7 ATG7 SIVA1 SIVA1 LOC102347143 LOC102347143 BAX BAX CASP3 CASP3 STAT3 STAT3 FASN FASN ATG5 ATG5 PIK3R1 PIK3R1 TP53 TP53 H3B8U3_LATCH H3B8U3_LATCH MTOR MTOR GYS1 GYS1 PCK1 PCK1 AKT1S1 AKT1S1 ACACA ACACA CPT1A CPT1A ACOX3 ACOX3 PKLR PKLR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ATG12Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (145 aa)
ATG7Autophagy related 7. (593 aa)
SIVA1SIVA1 apoptosis inducing factor. (168 aa)
LOC102347143Uncharacterized protein. (612 aa)
BAXUncharacterized protein. (223 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (290 aa)
STAT3Signal transducer and activator of transcription. (763 aa)
FASNFatty acid synthase. (2502 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (725 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (401 aa)
H3B8U3_LATCHSerine/threonine-protein kinase TOR. (1418 aa)
MTORMechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family. (1009 aa)
GYS1Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (721 aa)
PCK1Phosphoenolpyruvate carboxykinase 1. (622 aa)
AKT1S1AKT1 substrate 1. (285 aa)
ACACAAcetyl-CoA carboxylase alpha. (2312 aa)
CPT1ACarnitine palmitoyltransferase 1A; Belongs to the carnitine/choline acetyltransferase family. (772 aa)
ACOX3Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (708 aa)
PKLRPyruvate kinase; Belongs to the pyruvate kinase family. (530 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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