STRINGSTRING
ACADM ACADM HADHB HADHB COX4I1 COX4I1 ACADL ACADL KLF5 KLF5 ACAD9 ACAD9 HSP90B1 HSP90B1 PKM PKM HMGCS1 HMGCS1 E2F1 E2F1 MYCN MYCN PYGB PYGB CREB3L3 CREB3L3 TARS1 TARS1 FBP1 FBP1 FOXO1 FOXO1 GPX7 GPX7 HSP90AB1 HSP90AB1 PPARA PPARA HADHA HADHA EEF2 EEF2 GPX8 GPX8 PGD PGD H3B037_LATCH H3B037_LATCH HNF4A HNF4A GOT1 GOT1 PPARGC1A PPARGC1A PRDX3 PRDX3 SOD2 SOD2 GPX1 GPX1 GPX3 GPX3 ASS1 ASS1 ARG2 ARG2 PCK1 PCK1 PC PC CS CS G6PD G6PD PKLR PKLR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ACADMAcyl-CoA dehydrogenase medium chain. (424 aa)
HADHBHydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta; Belongs to the thiolase-like superfamily. Thiolase family. (459 aa)
COX4I1Cytochrome c oxidase subunit 4I1. (169 aa)
ACADLAcyl-CoA dehydrogenase long chain. (448 aa)
KLF5Kruppel like factor 5. (435 aa)
ACAD9Acyl-CoA dehydrogenase family member 9. (642 aa)
HSP90B1Heat shock protein 90 beta family member 1. (800 aa)
PKMPyruvate kinase; Belongs to the pyruvate kinase family. (539 aa)
HMGCS13-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (525 aa)
E2F1E2F transcription factor 1. (411 aa)
MYCNMYCN proto-oncogene, bHLH transcription factor. (417 aa)
PYGBAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (267 aa)
CREB3L3cAMP responsive element binding protein 3 like 3. (329 aa)
TARS1Threonyl-tRNA synthetase. (722 aa)
FBP1Fructose-bisphosphatase 1; Belongs to the FBPase class 1 family. (338 aa)
FOXO1Forkhead box O1. (633 aa)
GPX7Glutathione peroxidase; Belongs to the glutathione peroxidase family. (185 aa)
HSP90AB1Heat shock protein 90 alpha family class B member 1. (734 aa)
PPARAPeroxisome proliferator activated receptor alpha. (468 aa)
HADHAHydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha; Belongs to the enoyl-CoA hydratase/isomerase family. (766 aa)
EEF2Eukaryotic translation elongation factor 2, like 2. (873 aa)
GPX8Glutathione peroxidase; Belongs to the glutathione peroxidase family. (173 aa)
PGD6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (483 aa)
H3B037_LATCHGlutathione peroxidase; Belongs to the glutathione peroxidase family. (112 aa)
HNF4AHepatocyte nuclear factor 4 alpha. (465 aa)
GOT1Aspartate aminotransferase. (399 aa)
PPARGC1APPARG coactivator 1 alpha. (783 aa)
PRDX3Peroxiredoxin 3. (254 aa)
SOD2Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (223 aa)
GPX1Glutathione peroxidase; Belongs to the glutathione peroxidase family. (142 aa)
GPX3Glutathione peroxidase 3. (108 aa)
ASS1Argininosuccinate synthase 1. (441 aa)
ARG2Arginase. (363 aa)
PCK1Phosphoenolpyruvate carboxykinase 1. (622 aa)
PCPyruvate carboxylase. (722 aa)
CSCitrate synthase; Belongs to the citrate synthase family. (468 aa)
G6PDGlucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (430 aa)
PKLRPyruvate kinase; Belongs to the pyruvate kinase family. (530 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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