STRINGSTRING
TGFB2 TGFB2 TGFB1 TGFB1 HDAC7 HDAC7 CTSK CTSK HDAC4 HDAC4 EWSR1 EWSR1 CDKN1A CDKN1A HDAC3 HDAC3 LOC102360670 LOC102360670 CDH16 CDH16 COL21A1 COL21A1 STAT3 STAT3 RHEB RHEB TGFB3 TGFB3 HDAC5 HDAC5 LOC102352268 LOC102352268 SOCS3 SOCS3 NOS2 NOS2 DCN DCN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (415 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (401 aa)
HDAC7Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (873 aa)
CTSKCathepsin K; Belongs to the peptidase C1 family. (333 aa)
HDAC4Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1086 aa)
EWSR1EWS RNA binding protein 1. (666 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (171 aa)
HDAC3Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (428 aa)
LOC102360670Uncharacterized protein. (209 aa)
CDH16Cadherin 16, KSP-cadherin. (839 aa)
COL21A1Collagen, type XXI, alpha 1. (479 aa)
STAT3Signal transducer and activator of transcription. (763 aa)
RHEBRas homolog, mTORC1 binding. (184 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (409 aa)
HDAC5Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1084 aa)
LOC102352268Transforming growth factor beta; Belongs to the TGF-beta family. (414 aa)
SOCS3Suppressor of cytokine signaling 3. (205 aa)
NOS2Nitric oxide synthase; Produces nitric oxide (NO). (1126 aa)
DCNDecorin; May affect the rate of fibrils formation. (353 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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