STRINGSTRING
NOD2 NOD2 TLR3 TLR3 IFIH1 IFIH1 TBK1 TBK1 NOD1 NOD1 IRF3 IRF3 MYD88 MYD88 KCNH7 KCNH7 SLC4A10 SLC4A10 RIPK2 RIPK2 IRF8 IRF8 CYLD CYLD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NOD2Nucleotide binding oligomerization domain containing 2. (854 aa)
TLR3Toll like receptor 3; Belongs to the Toll-like receptor family. (766 aa)
IFIH1Interferon induced with helicase C domain 1. (731 aa)
TBK1TANK binding kinase 1. (675 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (830 aa)
IRF3Interferon regulatory factor 3. (481 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (286 aa)
KCNH7Potassium voltage-gated channel subfamily H member 7. (594 aa)
SLC4A10Anion exchange protein. (1097 aa)
RIPK2Receptor interacting serine/threonine kinase 2. (567 aa)
IRF8Interferon regulatory factor 8. (430 aa)
CYLDCYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family. (959 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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